ID G1QB47_MYOLU Unreviewed; 783 AA.
AC G1QB47;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Calmodulin regulated spectrin associated protein 1 {ECO:0000313|Ensembl:ENSMLUP00000020930.1};
GN Name=CAMSAP1 {ECO:0000313|Ensembl:ENSMLUP00000020930.1};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000020930.1, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000020930.1, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000020930.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAPE02057704; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1QB47; -.
DR Ensembl; ENSMLUT00000025147.1; ENSMLUP00000020930.1; ENSMLUG00000003261.2.
DR GeneTree; ENSGT00950000182975; -.
DR HOGENOM; CLU_004833_0_0_1; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0005516; F:calmodulin binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0030507; F:spectrin binding; IEA:InterPro.
DR GO; GO:0031175; P:neuron projection development; IEA:InterPro.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR InterPro; IPR032940; CAMSAP.
DR InterPro; IPR022613; CAMSAP-like_CH_dom.
DR InterPro; IPR031372; CAMSAP_CC1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR PANTHER; PTHR21595:SF3; CALMODULIN-REGULATED SPECTRIN-ASSOCIATED PROTEIN 1; 1.
DR PANTHER; PTHR21595; UNCHARACTERIZED; 1.
DR Pfam; PF17095; CAMSAP_CC1; 1.
DR Pfam; PF11971; CAMSAP_CH; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR PROSITE; PS50021; CH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001074}.
FT DOMAIN 176..291
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REGION 308..432
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 550..578
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 665..696
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 715..760
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..408
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 666..687
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 715..729
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 783 AA; 86818 MW; AA9A57942B5D2CF4 CRC64;
GSDNIPEDLR DPFYIDQYEQ EHIKPPVIKL LLAGELYCRV CSLILKGDQA AALQGHQSVI
QALSRKGIYV MESDDTPVTD PDLSHAPIKM SAHMAMVDAL MMAYTVEMIS IEKVVASVKR
FSTFSASKEL PYDLEDAMVF WVNKVNLKMR EITEKEGKLR QQFLESPAHQ KSPSKWYWKL
VPVRYRREHL SARQPPYFPL LEDLMRDGSD GAALLAVVHY YCPKHMKLDD VCLKEVMSMA
DSLYNIRLLR EFSNEYLNRC FYLTLEDMLY APLVLKPNVM VFIAELFWWF ENVRPDFVQP
RDVQELKDAK TVSHQKSSRP PVPISNATKR SFLGGPAAAS PAEPPAPAQP PAEGCPRQHL
HPEEPDPLGR GASAFSPSHP LLPLRQRQQR AAPGEDPPDE RHRSSSLTRV DGQPRGAAVA
WPEKKHRPAS QPAPFALHHT ASCDADPGSG DSVSLARSIS KDSLASNILP LTPQNQPQTP
ALRASGKSLL NNVDIEDEDE ELMAIVRTNG AQSKLDSFFL EPLMPAVLRP AKEKQAVSKE
DECGEGRLRG CAARRPSEGP PLGRRKAPGS SGTRDLNRTF TPISSVELCA EGQSPDGFFL
HVARADEAPE GGLHGTRARS PLARDPEPWT VLRQDSDSDV ADLEEAEHDF LGEDLPVLMG
RYAGEEESAK LQEDMQVKEH EDKDGASGRS SPCLSTFSQF SGGFVAAGRA RMPTLQRAMS
QSPVRAASQK TTPDGLGELP RAPPDPRGRL GPRQPPGLGS WVQLHMQLEE KRRAIEAQKK
KME
//
