ID G1QJF7_NOMLE Unreviewed; 793 AA.
AC G1QJF7;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=EMAP like 1 {ECO:0000313|Ensembl:ENSNLEP00000001051.2};
GN Name=EML1 {ECO:0000313|Ensembl:ENSNLEP00000001051.2};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000001051.2, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000001051.2, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000001051.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the WD repeat EMAP family.
CC {ECO:0000256|ARBA:ARBA00006489}.
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DR EMBL; ADFV01087217; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01087218; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01087219; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01087220; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01087221; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01087222; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01087223; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01087224; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01087225; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01087226; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1QJF7; -.
DR Ensembl; ENSNLET00000001113.2; ENSNLEP00000001051.2; ENSNLEG00000000861.2.
DR eggNOG; KOG2106; Eukaryota.
DR GeneTree; ENSGT00940000153887; -.
DR HOGENOM; CLU_011754_0_0_1; -.
DR TreeFam; TF317832; -.
DR Proteomes; UP000001073; Chromosome 22a.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR CDD; cd21947; TD_EMAP1; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR005108; HELP.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13720:SF22; ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 1; 1.
DR PANTHER; PTHR13720; WD-40 REPEAT PROTEIN; 1.
DR Pfam; PF03451; HELP; 1.
DR Pfam; PF00400; WD40; 5.
DR SMART; SM00320; WD40; 9.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 169..240
FT /note="HELP"
FT /evidence="ECO:0000259|Pfam:PF03451"
FT REPEAT 517..549
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 646..677
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 758..793
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 72..160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 72..89
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 107..123
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 134..150
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 793 AA; 87490 MW; BD715062F1B063D0 CRC64;
GQYDDSASAA SSMEVTDRIA SLEQRVQMQE DDIQLLKSAL ADVVRRLNIT EEQQAVLNRK
GPTKARPLMQ TLPLRTTVNN GTVLPKKPTG SLPSPSGVRK ETAVPATKSN IKRTSSSERV
SPGGRRESNG DSKGNRNRTG STSSSSSGKK NSESKPKEPV FSAEEGYVKM FLRGRPVTMY
MPKDQVDSYS LEAKVELPTK RLKLEWVYGY RGRDCRNNLY LLPTGETVYF IASVVVLYNV
EEQLQRHYAG HNDDVKCLAV HPDRITIATG QVAGTSKDGK QLPPHVRIWD SVTLNTLHVI
GIGFFDRAVT CIAFSKSNGG TNLCAVDDSN DHVLSVWDWQ KEEKLADVKC SNEAVFAADF
HPTDTNIIVT CGKSHLYFWT LEGSSLNKKQ GLFEKQEKPK FVLCVTFSDT ITGDSSGNIL
VWGKGTNRIS YAVQGAHEGG IFALCMLRDG TLVSGGGKDR KLISWSGNYQ KLRKTEIPEQ
FGPIRTVAEG KGDVILIGTT RNFVLQGTLS GDFTPITQGH TDELWGLAIH ASKPQFLTCG
HDKHATLWDS VDHRPDWDNL IEDPAQSSGF HPSGSVVAVG TLTGRWFVFD TETKDLVTVH
TDGNEQLSVM RYSPDGNFLA IGSHDNCIYI YGVSDNGRKY TRVGKCSGHS SFITHLDWSV
NSQFLVSNSG DYEILYWVPS ACKQVVSVET TRDIEWATYT CTLGFHVFGV WPEGSDGTDI
NAVCRAHEKK LLSTGDDFGK VHLFSYPCSQ FRAPSHIYGG HSSHVTNVDF LCEDSHLIST
GGKDTSIMQW RVI
//
