ID G1QK31_NOMLE Unreviewed; 469 AA.
AC G1QK31;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=XK-related protein {ECO:0000256|RuleBase:RU910716};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000001276.2, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000001276.2, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000001276.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) = a 1,2-diacyl-
CC sn-glycero-3-phospho-L-serine(out); Xref=Rhea:RHEA:38663,
CC ChEBI:CHEBI:57262; Evidence={ECO:0000256|ARBA:ARBA00024479};
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU910716}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU910716}.
CC -!- SIMILARITY: Belongs to the XK family. {ECO:0000256|ARBA:ARBA00008789,
CC ECO:0000256|RuleBase:RU910716}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ADFV01167156; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01167157; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01167158; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01167159; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01167160; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01167161; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01167162; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01167163; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01167164; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01167165; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1QK31; -.
DR STRING; 61853.ENSNLEP00000001276; -.
DR Ensembl; ENSNLET00000001352.2; ENSNLEP00000001276.2; ENSNLEG00000001093.2.
DR eggNOG; KOG4790; Eukaryota.
DR GeneTree; ENSGT01070000253766; -.
DR HOGENOM; CLU_028534_0_0_1; -.
DR InParanoid; G1QK31; -.
DR OMA; LWDGLWI; -.
DR TreeFam; TF316454; -.
DR Proteomes; UP000001073; Chromosome 16.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR018629; XK-rel.
DR PANTHER; PTHR16024; XK-RELATED PROTEIN; 1.
DR PANTHER; PTHR16024:SF16; XK-RELATED PROTEIN 4; 1.
DR Pfam; PF09815; XK-related; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU910716};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Transmembrane {ECO:0000256|RuleBase:RU910716};
KW Transmembrane helix {ECO:0000256|RuleBase:RU910716}.
FT TRANSMEM 71..90
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 151..170
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 191..212
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 218..238
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 250..265
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 277..296
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 308..331
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT REGION 1..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..57
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 469 AA; 53099 MW; BFEDB94D5577B5FC CRC64;
ASRRPQPGAD CKTVVGGGSA VGEGEARPST PQRQASNASK SNIAAASSGS NSSGATRASG
KHRSASCSFC IWLLQSLIHI LQLGQIWRYF HTIYLGIRSR QSGENDRWRF YWKMVYEYAD
VSMLHLLATF LESAPQLVLQ LCIIVQTHSL QALQGFTAAA SLVSLAWALA SYQKALRDSR
DDKKPISYMA VIIQFCWHFF TIAARVITFA LFASVFQLYF GIFIVLHWCI MTFWIVHCET
EFCITKWEEI VFDMVVGIIY IFSWFNVKEG RTRCRLFIYY FVILLENTAL SALWYLYKAP
QIADAFAIPA LCVVFSSFLT GVVFMLMYYA FFHPNGPRFG QSPSCACEDP AAAFTLPPDV
ATSTLRSISN NRSVVSDRDQ KFAERDGCVP VFQVRPTAPS TPSSRPPRIE ESVIKIDLFR
NRYPAWERHV LDRSLRKAIL AFECSPSPPR LQYKDDALIQ ERLEYETTL
//
