ID G1QK56_NOMLE Unreviewed; 496 AA.
AC G1QK56;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Matrilin 1 {ECO:0000313|Ensembl:ENSNLEP00000001301.1};
GN Name=MATN1 {ECO:0000313|Ensembl:ENSNLEP00000001301.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000001301.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000001301.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000001301.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01094410; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003276380.1; XM_003276332.2.
DR AlphaFoldDB; G1QK56; -.
DR STRING; 61853.ENSNLEP00000001301; -.
DR Ensembl; ENSNLET00000001377.2; ENSNLEP00000001301.1; ENSNLEG00000001107.2.
DR GeneID; 100581319; -.
DR KEGG; nle:100581319; -.
DR CTD; 4146; -.
DR eggNOG; KOG1217; Eukaryota.
DR GeneTree; ENSGT00940000159638; -.
DR HOGENOM; CLU_008905_7_0_1; -.
DR InParanoid; G1QK56; -.
DR OMA; ICIEEDP; -.
DR OrthoDB; 1453590at2759; -.
DR TreeFam; TF330078; -.
DR Proteomes; UP000001073; Chromosome 12.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd01475; vWA_Matrilin; 2.
DR Gene3D; 1.20.5.30; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR036337; Matrilin_cc_sf.
DR InterPro; IPR019466; Matrilin_coiled-coil_trimer.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR24020:SF16; CARTILAGE MATRIX PROTEIN; 1.
DR PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR Pfam; PF14670; FXa_inhibition; 1.
DR Pfam; PF10393; Matrilin_ccoil; 1.
DR Pfam; PF00092; VWA; 2.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00181; EGF; 1.
DR SMART; SM00179; EGF_CA; 1.
DR SMART; SM01279; Matrilin_ccoil; 1.
DR SMART; SM00327; VWA; 2.
DR SUPFAM; SSF58002; Chicken cartilage matrix protein; 1.
DR SUPFAM; SSF53300; vWA-like; 2.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50234; VWFA; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..496
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003419438"
FT DOMAIN 41..216
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 275..447
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
SQ SEQUENCE 496 AA; 53755 MW; 4298AFB9B8C18DCF CRC64;
MRVLSGTSLM LCSLLLLLQA PCSPGLAPQS TGHLCRTRPT DLVFVVDSSR SVRPVEFEKV
KVFLSQVIQS LDVGPNATRV GMVNYASTVK QEFSLRAHVS KAALLQAVRR IQPLSTGTMT
GLAIQFAITK AFSDAEGGRS RSPDISKVVI VVTDGRPQDS VQDVSARARA SGVELFAIGV
GRVDKATLRQ IASEPQDEHV DYVESYSVIE KLSRKFQEAF CVVSDLCATG DHDCEQVCIS
SPGSYTCACH EGFTLNSDGK TCNVCSGGGG SSATDLVFLI DGSKSVRPEN FELVKKFINQ
IVDTLDVSDK LAQVGLVQYS SSVRQEFPLG RFHTKKDIKA AVRNMSYMEK GTMTGAALKY
LIDNSFTVSS GARPGAQKVG IVFTDGRSQD YINDAAKKAK DLGFKMFAVG VGNAVEDELR
EIASEPVAEH YFYTADFKTI NQIGKKLQKK ICVEEDPCAC ESLVKFQAKV EGLLQALTRK
LEAVSKRLAI LENTVV
//
