ID G1QKA5_NOMLE Unreviewed; 184 AA.
AC G1QKA5;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Endothelial cell specific molecule 1 {ECO:0000313|Ensembl:ENSNLEP00000001350.1};
GN Name=ESM1 {ECO:0000313|Ensembl:ENSNLEP00000001350.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000001350.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000001350.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000001350.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01030631; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1QKA5; -.
DR STRING; 61853.ENSNLEP00000001350; -.
DR Ensembl; ENSNLET00000001428.2; ENSNLEP00000001350.1; ENSNLEG00000001154.2.
DR eggNOG; KOG1218; Eukaryota.
DR GeneTree; ENSGT00390000018810; -.
DR HOGENOM; CLU_103395_0_0_1; -.
DR InParanoid; G1QKA5; -.
DR OMA; TAWSAKY; -.
DR OrthoDB; 5341363at2759; -.
DR Proteomes; UP000001073; Chromosome 18.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0005171; F:hepatocyte growth factor receptor binding; IEA:Ensembl.
DR GO; GO:0005178; F:integrin binding; IEA:Ensembl.
DR GO; GO:0008284; P:positive regulation of cell population proliferation; IEA:Ensembl.
DR GO; GO:1902204; P:positive regulation of hepatocyte growth factor receptor signaling pathway; IEA:Ensembl.
DR GO; GO:0002040; P:sprouting angiogenesis; IEA:Ensembl.
DR Gene3D; 4.10.40.20; -; 1.
DR InterPro; IPR038850; ESM1.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR000867; IGFBP-like.
DR PANTHER; PTHR15428:SF0; ENDOTHELIAL CELL-SPECIFIC MOLECULE 1; 1.
DR PANTHER; PTHR15428; ENDOTHELIAL CELL-SPECIFIC MOLECULE 1 ESM-1; 1.
DR Pfam; PF00219; IGFBP; 1.
DR SMART; SM00121; IB; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS51323; IGFBP_N_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..184
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003420191"
FT DOMAIN 24..102
FT /note="IGFBP N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51323"
SQ SEQUENCE 184 AA; 20086 MW; 04F1153EC74BC8D9 CRC64;
MKSVLLLTTL LVPAHLVAAW SNNYAVDCPQ HCDSSECKSS PRCKRTVLDD CGCCRVCAAG
RGETCYRTVS GMDGMKCGPG LRCQPSNGED PFGEEFGICK DCPYGTFGMD CRETCNCQSG
ICDRGTGKCL KFPFFQYSVT KSSNRFVSLT ERDMASGDGN VVREEVVKDN AAGSPVMRKW
LNPR
//
