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Database: UniProt
Entry: G1QQF9_NOMLE
LinkDB: G1QQF9_NOMLE
Original site: G1QQF9_NOMLE 
ID   G1QQF9_NOMLE            Unreviewed;       457 AA.
AC   G1QQF9;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 3.
DT   18-SEP-2019, entry version 50.
DE   SubName: Full=Potassium voltage-gated channel subfamily J member 16 {ECO:0000313|Ensembl:ENSNLEP00000003177};
GN   Name=KCNJ16 {ECO:0000313|Ensembl:ENSNLEP00000003177};
OS   Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates
OS   leucogenys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hylobatidae; Nomascus.
OX   NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000003177};
RN   [1] {ECO:0000313|Ensembl:ENSNLEP00000003177}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
RN   [2] {ECO:0000313|Ensembl:ENSNLEP00000003177}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Gibbon Genome Sequencing Consortium;
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   EMBL; ADFV01092028; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01092029; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 61853.ENSNLEP00000003177; -.
DR   Ensembl; ENSNLET00000003337; ENSNLEP00000003177; ENSNLEG00000002620.
DR   eggNOG; KOG3827; Eukaryota.
DR   eggNOG; ENOG410XQ62; LUCA.
DR   GeneTree; ENSGT00970000193347; -.
DR   InParanoid; G1QQF9; -.
DR   TreeFam; TF313676; -.
DR   Proteomes; UP000001073; Chromosome 14.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR008061; K_chnl_inward-rec_Kir5.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   PANTHER; PTHR11767:SF24; PTHR11767:SF24; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 1.
DR   PRINTS; PR01678; KIR5CHANNEL.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001073};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM    113    135       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    184    209       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       77    213       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      221    387       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   SITE        200    200       Role in the control of polyamine-mediated
FT                                channel gating and in the blocking by
FT                                intracellular magnesium.
FT                                {ECO:0000256|PIRSR:PIRSR005465-1}.
SQ   SEQUENCE   457 AA;  52585 MW;  B5A0EB0A346472CC CRC64;
     VILQKCRKVL TENPNQEIAT RPEFLLLQNS PRSLRAQQRM SYYGSSYHIV NVDAKYPGYP
     PEHIIAEKRR ARRRLLHKDG SCNVYFKHIF GEWGSYVVDI FTTLVDTKWR HMFVIFSLSY
     ILSWLIFGSV FWLIAFHHGD LVNDPDITPC VDNVHSFTGA FLFSLETQTT IGYGYRCVTE
     ECPVAVLMVI LQSILSCIIN TFIIGAALAK MATARKRAQT IRFSYFALIG MRDGKLCLMW
     RIGDFRPNHV VEGTVRAQLL RYTEDSEGRM TMAFKDLKLV NDQIILVTPV TIVHEIDHES
     PLYALDRKAV AKDNFEILVT FIYTGDSTGT SHQSRSSYVP REILWGHRFN DVLEVKRKYY
     KVNCLQFEGS VEVYAPFCSA KQLDWKDQQL HIEKAPPVRE SYTSDTNARR RSFSAVAIVS
     SCENPEETTT SATHEYRETP YHKALLTLNR ISVESQM
//
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