ID G1QT32_NOMLE Unreviewed; 526 AA.
AC G1QT32;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Butyrophilin subfamily 1 member A1 {ECO:0000313|Ensembl:ENSNLEP00000004100.1};
GN Name=BTN1A1 {ECO:0000313|Ensembl:ENSNLEP00000004100.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000004100.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000004100.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000004100.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. BTN/MOG family.
CC {ECO:0000256|ARBA:ARBA00007591}.
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DR EMBL; ADFV01016358; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003263346.1; XM_003263298.1.
DR AlphaFoldDB; G1QT32; -.
DR STRING; 61853.ENSNLEP00000004100; -.
DR Ensembl; ENSNLET00000004303.2; ENSNLEP00000004100.1; ENSNLEG00000003349.2.
DR GeneID; 100604436; -.
DR KEGG; nle:100604436; -.
DR CTD; 696; -.
DR eggNOG; ENOG502QSRZ; Eukaryota.
DR GeneTree; ENSGT00940000161530; -.
DR HOGENOM; CLU_013137_22_2_1; -.
DR InParanoid; G1QT32; -.
DR OMA; AHMELRW; -.
DR OrthoDB; 2943983at2759; -.
DR TreeFam; TF331083; -.
DR Proteomes; UP000001073; Chromosome 8.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd05713; IgV_MOG_like; 1.
DR CDD; cd15819; SPRY_PRY_BTN1_2; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR037958; SPRY/PRY_BTN1/2.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR24100; BUTYROPHILIN; 1.
DR PANTHER; PTHR24100:SF145; BUTYROPHILIN SUBFAMILY 1 MEMBER A1; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF07686; V-set; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00409; IG; 2.
DR SMART; SM00406; IGv; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..526
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003419755"
FT TRANSMEM 246..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 22..138
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 148..234
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 285..479
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 495..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 526 AA; 58824 MW; 39C219A8CA1CDFB4 CRC64;
MAVFASSGLP RCLLTLILLQ LPKLDSAPFD VIGPPEPILS IVGEDAELPC RLSPNASAEH
LELRWFRKKV SPAVLVHRDG REQEAEQMPE YRGRATLVQD GIAKGRVALR IRGVRVSDDG
EYTCFIREDG SYEEALVHLK VAALGSDPYI SMQVQENGEI RLECTSVGWY PEPQVQWRSS
KGEKFPSTSE SRNPDEEGLF TVAASVTIRD TSAKNVSCYI QNLLLGQEKE VEISIPASSL
PRLTPWIVAV AVILMALGFL TIGSIFFSWR LYNERSRERR NEFSSKERLL EELKWKKATL
HAVDVTLDPD TAHPHLFLYE DSKSVRLEDS RQKLPEKPER FDSWPCVLGH ETFTSGRHYW
EVEVGDRTDW AIGVCRENVM KKGFDPMTPE NGFWAVELYG NGYWALTPLR TPLPLAGPPH
RVGIFLDYES GDISFYNMND GSNIYTFSNV SFSGPLRPFF CLWSSGKKPL TICPIAEGPE
GVTVIANAQD LSKEIPLSPM GEDSAPRDAD TLHSKLIPTQ PSQGAP
//
