ID G1QXH8_NOMLE Unreviewed; 449 AA.
AC G1QXH8;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=EF-hand calcium binding domain 3 {ECO:0000313|Ensembl:ENSNLEP00000005649.2};
GN Name=EFCAB3 {ECO:0000313|Ensembl:ENSNLEP00000005649.2};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000005649.2, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000005649.2, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000005649.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01061395; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01061396; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01061397; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01061398; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01061399; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01061400; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01061401; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003270847.2; XM_003270799.3.
DR AlphaFoldDB; G1QXH8; -.
DR STRING; 61853.ENSNLEP00000005649; -.
DR Ensembl; ENSNLET00000005942.2; ENSNLEP00000005649.2; ENSNLEG00000004662.2.
DR GeneID; 100605800; -.
DR KEGG; nle:100605800; -.
DR CTD; 146779; -.
DR eggNOG; KOG0027; Eukaryota.
DR GeneTree; ENSGT00940000161358; -.
DR HOGENOM; CLU_055753_0_0_1; -.
DR InParanoid; G1QXH8; -.
DR OMA; QMQAFQD; -.
DR OrthoDB; 4632293at2759; -.
DR TreeFam; TF328393; -.
DR Proteomes; UP000001073; Chromosome 19.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR22656:SF1; EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 13; 1.
DR PANTHER; PTHR22656; UNCHARACTERIZED; 1.
DR Pfam; PF13833; EF-hand_8; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 135..170
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 416..449
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 416..430
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 449 AA; 51469 MW; 941F1B03A8A942AE CRC64;
MKELMPHLTF NGNGKINVNS VMEGLKKFKP KGMVTLHKLK TANDIKDRVT GHMAVSEVKP
KLKLNPLIKV PISHSKRDRD LPGSLQCQLQ HKEKKLSASQ MAAFQDAYNF FNKDKTGCID
FHGLMCTVAK LGMNLTKHDV YNELKCADID RDGKVNFSDF IKVLTDKNLF LKAVVPEKET
CLDLAGNPGI LLFEILSRLL ETSALPRKSI KEIVSYFQRK FQHTCPGMLW SPYTMGYGKR
TLKPDICTPP SSSMAAFANA ARIAIMKEND LFKFLEELKR CNPGSDSPYS KIPIFPLLPN
VDGVVMGKPF KDMQKLEMLR RKEPLNFFED YFFHKRDWKT QVKRATDTYN LGIALEHRKE
MLNLWQKIRG DLIGIDSRNE SFYDTFSTYT WSWNVCQELL SPKDLRLYDA YVNRNSSHNS
RSSSSSDTSE CDTDSGRKRK WKGLKGFQQ
//
