ID G1QXN1_NOMLE Unreviewed; 207 AA.
AC G1QXN1;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Interferon kappa {ECO:0000313|Ensembl:ENSNLEP00000005702.1};
GN Name=IFNK {ECO:0000313|Ensembl:ENSNLEP00000005702.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000005702.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000005702.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000005702.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the alpha/beta interferon family.
CC {ECO:0000256|ARBA:ARBA00011033, ECO:0000256|RuleBase:RU000436}.
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DR RefSeq; XP_003281871.1; XM_003281823.1.
DR AlphaFoldDB; G1QXN1; -.
DR STRING; 61853.ENSNLEP00000005702; -.
DR Ensembl; ENSNLET00000005998.2; ENSNLEP00000005702.1; ENSNLEG00000004712.2.
DR eggNOG; ENOG502SQGR; Eukaryota.
DR GeneTree; ENSGT01000000214430; -.
DR HOGENOM; CLU_109427_1_0_1; -.
DR InParanoid; G1QXN1; -.
DR OMA; NSFPVEC; -.
DR TreeFam; TF336177; -.
DR Proteomes; UP000001073; Unplaced.
DR GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
DR GO; GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.
DR GO; GO:0005132; F:type I interferon receptor binding; IEA:Ensembl.
DR GO; GO:0019221; P:cytokine-mediated signaling pathway; IEA:Ensembl.
DR GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:Ensembl.
DR Gene3D; 1.20.1250.10; -; 1.
DR InterPro; IPR009079; 4_helix_cytokine-like_core.
DR InterPro; IPR000471; Interferon_alpha/beta/delta.
DR PANTHER; PTHR11691:SF6; INTERFERON KAPPA; 1.
DR PANTHER; PTHR11691; TYPE I INTERFERON; 1.
DR Pfam; PF00143; Interferon; 1.
DR PRINTS; PR00266; INTERFERONAB.
DR SMART; SM00076; IFabd; 1.
DR SUPFAM; SSF47266; 4-helical cytokines; 1.
DR PROSITE; PS00252; INTERFERON_A_B_D; 1.
PE 3: Inferred from homology;
KW Antiviral defense {ECO:0000256|ARBA:ARBA00023118,
KW ECO:0000256|RuleBase:RU000436}; Cytokine {ECO:0000256|RuleBase:RU000436};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073}.
SQ SEQUENCE 207 AA; 25271 MW; 91C285110184AD58 CRC64;
MSTNPDMIQK CLWLEFLTGM FIAGTLSLDC NLLNVHLRRV TWQNLRHLSS MSNSFPVECL
RENIAFELPQ EFLQYTQPMK RDIKKAFYEM SLQAFNIFSQ HTFKYWKERY LKQIQIGLDQ
QAEYLNQCLE EDENDNEDMK EMKENEMKPS EARVPRLSNL ELRRYFNRID NFLKEKKYSD
CAWEIVRVEI RRCLYYFYKF TALFRRK
//
