ID G1QXZ7_NOMLE Unreviewed; 339 AA.
AC G1QXZ7;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Ret finger protein like 2 {ECO:0000313|Ensembl:ENSNLEP00000005818.2};
GN Name=RFPL2 {ECO:0000313|Ensembl:ENSNLEP00000005818.2};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000005818.2, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000005818.2, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000005818.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ADFV01177846; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01177847; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1QXZ7; -.
DR STRING; 61853.ENSNLEP00000005818; -.
DR Ensembl; ENSNLET00000006124.2; ENSNLEP00000005818.2; ENSNLEG00000004795.3.
DR eggNOG; KOG2177; Eukaryota.
DR GeneTree; ENSGT00940000163408; -.
DR HOGENOM; CLU_013137_7_1_1; -.
DR InParanoid; G1QXZ7; -.
DR OMA; GLLCYCC; -.
DR Proteomes; UP000001073; Chromosome 7b.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15821; SPRY_PRY_RFPL; 1.
DR CDD; cd16621; vRING-HC-C4C4_RFPL; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR022723; RDM_domain_RFPL.
DR InterPro; IPR037960; SPRY/PRY_RFPL.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR24103:SF691; B30.2_SPRY DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF11002; RDM; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF15227; zf-C3HC4_4; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 128..322
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..40
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 339 AA; 37993 MW; B49ECD2AA814D5F2 CRC64;
VIRLEGVEGR HPVGGGNLTN KRPSCAPSPQ DLSSQWKQQE DRGASSRRVD MAALFQEASS
CPVCSHYLEK PMSLECGCAV CLKCINSLQK EPHGQDLLCC CCSMVSQRNK IRPNRHLERL
VSHIKELEPK LKKILQMNPR MRKFQVDMTL DADTANNFLL ISDDLRSVRS GRIRQNRQDL
AERFDFSICV LGSPRFTCGR HYWEVDVGTS TEWDLGVCRE SVHRKGRIQL TTERGFWTVS
LRDGSRLSAS TVPLTFLFVD RKLQRVGIFL DMGMQNVSFF DAEGGSHVYT FRSVSAEEPL
RPFLAPSIPP NGDQGVLSIC PVMNSGTTDA PIHPGEAKQ
//
