ID G1R0G0_NOMLE Unreviewed; 755 AA.
AC G1R0G0;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=MTSS I-BAR domain containing 1 {ECO:0000313|Ensembl:ENSNLEP00000006681.1};
GN Name=MTSS1 {ECO:0000313|Ensembl:ENSNLEP00000006681.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000006681.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000006681.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000006681.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01168597; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01168598; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01168599; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01168600; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01168601; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01168602; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01168603; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01168604; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01168605; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01168606; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003256235.1; XM_003256187.2.
DR AlphaFoldDB; G1R0G0; -.
DR Ensembl; ENSNLET00000007016.2; ENSNLEP00000006681.1; ENSNLEG00000005496.2.
DR GeneID; 100582996; -.
DR KEGG; nle:100582996; -.
DR CTD; 9788; -.
DR eggNOG; ENOG502QRG4; Eukaryota.
DR GeneTree; ENSGT00950000183156; -.
DR HOGENOM; CLU_004805_2_0_1; -.
DR OrthoDB; 3875239at2759; -.
DR TreeFam; TF320619; -.
DR Proteomes; UP000001073; Chromosome 16.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0007009; P:plasma membrane organization; IEA:InterPro.
DR CDD; cd07643; I-BAR_IMD_MIM; 1.
DR CDD; cd22060; WH2_MTSS1; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR013606; I-BAR_dom.
DR InterPro; IPR030127; MTSS1/MTSS2.
DR InterPro; IPR003124; WH2_dom.
DR PANTHER; PTHR15708; ACTIN BUNDLING/MISSING IN METASTASIS-RELATED; 1.
DR PANTHER; PTHR15708:SF10; PROTEIN MTSS 1; 1.
DR Pfam; PF08397; IMD; 1.
DR Pfam; PF02205; WH2; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR PROSITE; PS51338; IMD; 1.
DR PROSITE; PS51082; WH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001073}.
FT DOMAIN 1..250
FT /note="IMD"
FT /evidence="ECO:0000259|PROSITE:PS51338"
FT DOMAIN 727..744
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT REGION 139..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 255..305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 327..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 428..470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 490..513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 563..755
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 139..157
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 614..634
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 651..670
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 685..701
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 755 AA; 82225 MW; 76E5F993FCBA9287 CRC64;
MEAVIEKECS ALGGLFQTII SDMKGSYPVW EDFINKAGKL QSQLRTTVVA AAAFLDAFQK
VADMATNTRG GTREIGSALT RMCMRHRSIE AKLRQFSSAL IDCLINPLQE QMEEWKKVAN
QLDKDHAKEY KKARQEIKKK SSDTLKLQKK AKKGRGDIQP QLDSALQDVN DKYLLLEETE
KQAVRKALIE ERGRFCTFIS MLRPVIEEEI SMLGEITHLQ TISEDLKSLT MDPHKLPSSS
EQVILDLKGS DYSWSYQTPP SSPSTTMSRK SSVCSSLNSV NSSDSRSSGS HSHSPSSHYR
YRSSNLAQQA PVRLSSVSSH DSGFISQDAF QSKSPSPMPP EAPNQLSNGF SHYSLSSESH
VGPTGAGLFP HCLPASRLLP RVTSVHLPDY AHYYTIGPGM FPSSQIPSWK DWAKPGPYDQ
PLVNTLQRRK EKREPDPNGG GPTTASGPPA AAEEAQRPRS MTVSAATRPG EEMEACEELA
LALSRGLQLD TQRSSRDSLQ CSSGYSTQTT TPCCSEDTIP SQVSDYDYFS VSGDQEADQQ
EFDKSSTIPR NSDISQSYRR MFQAKRPAST AGLPTTLGPA MVTPGVATIR RTPSTKPSVR
RGTIGAGPIP IKTPVIPVKT PTVPDLPGVL PAPPDGPEER GEHSPESPSV GEGPQGVTSM
PSSMWSGQAS VNPPLPGPKP SIPEEHRQAI PESEAEDQER EPPSATVSPG QIPESDPADL
SARDTPQGED MLNAIRRGVK LKKTTTNDRS APRFS
//
