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Database: UniProt
Entry: G1R0P2_NOMLE
LinkDB: G1R0P2_NOMLE
Original site: G1R0P2_NOMLE 
ID   G1R0P2_NOMLE            Unreviewed;      1542 AA.
AC   G1R0P2;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 2.
DT   08-MAY-2019, entry version 48.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSNLEP00000006763};
GN   Name=NWD1 {ECO:0000313|Ensembl:ENSNLEP00000006763};
OS   Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates
OS   leucogenys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hylobatidae; Nomascus.
OX   NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000006763};
RN   [1] {ECO:0000313|Ensembl:ENSNLEP00000006763}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
RN   [2] {ECO:0000313|Ensembl:ENSNLEP00000006763}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Gibbon Genome Sequencing Consortium;
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; ADFV01089975; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01089976; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01089977; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01089978; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01089979; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01089980; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01089981; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01089982; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01089983; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01089984; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 61853.ENSNLEP00000006763; -.
DR   Ensembl; ENSNLET00000007102; ENSNLEP00000006763; ENSNLEG00000005585.
DR   eggNOG; KOG3602; Eukaryota.
DR   eggNOG; COG2319; LUCA.
DR   GeneTree; ENSGT00940000161635; -.
DR   InParanoid; G1R0P2; -.
DR   TreeFam; TF332647; -.
DR   Proteomes; UP000001073; Chromosome 10.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   Gene3D; 2.130.10.10; -; 3.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR017986; WD40_repeat_dom.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF00400; WD40; 3.
DR   SMART; SM00320; WD40; 9.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 2.
DR   PROSITE; PS50082; WD_REPEATS_2; 2.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001073};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW   WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT   DOMAIN      891   1022       WD_REPEATS_REGION. {ECO:0000259|PROSITE:
FT                                PS50294}.
FT   REPEAT      898    932       WD. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00221}.
FT   DOMAIN     1362   1448       WD_REPEATS_REGION. {ECO:0000259|PROSITE:
FT                                PS50294}.
FT   REPEAT     1362   1396       WD. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00221}.
SQ   SEQUENCE   1542 AA;  171647 MW;  5AB540107CD746EA CRC64;
     QRGKPCRTFC QKHGLMFEVV DLRWGIRNIE ATDCLTTELC LEEVDRCWKT SIGPAFVALI
     GDQYGPCLVP SRIDEKEWEV LRAHLTARPS DLELVARHFQ RDENAVPPTY ILQAPGTGEA
     CEPEEANLTS VLRSGAQKAW RLGLITQEQW QRYHRSVIEW EIERGLLSSE DRDQGATVFL
     REIQDLHKHI LEDCALRMVD RLADGCLGTD AQNLLSSLKG HITDMHPGVL KAHRLPWSRD
     LVNPKNKTHA RYLKELGEQF VVRANHQVLT RLRELDTAGQ ELAWLYQEIR HHLWQSSEIT
     QTFCGRQELL AQLGQQLRHD DSKQHTPLVL FGPPGIGKTA LMCKLAEQMP RLLGHKTVTI
     LRLLGTSQMS SDARSLLKSI CFQVCLAYGL PLPPAQVLDT HTRVVQFFHT LLHTVSCRNF
     ESLVLLLDAM DDLDSVRHAR RVPWLPLNCP PSVHLILSAC SGALGVLDTL QRVLLDPEAY
     WEVKPLSGNQ GQEMIQLLLA AARRTLRPVH TDLLWASLPE CGNPGQLRLA FEEARRWASF
     TVPASLATTA EEATHQLCAR LEQTHGRLLV AHVLGYVVSS RHGLSEAELK DVLSLDDEVL
     QDVYRDWTPP SKELLRFPPL LWVRLRRDLE YYLARRPVDG FTLLAIAHRQ LVEVVRERYL
     SGSERAKRHG VLADFFSGTW SQGTKKLITL PLVGKPLNLD RKVAPQPLWF SDAVANLRKL
     KELPYHLLHS GRLEELKQEV LGSMSWISCR GISGGIEDLL DDFDLCAPHL DSPEVGLVRE
     ALQLCRPAVE LRGMERSLLY TELLARLHFF ATSHPALVGQ LCQQAQNWFR LCAHPVLVPL
     GGFLQPPGGP LRATLISLCH PGWSAMGISK LTIILIVARS KCSQLIYSPL PWPASGEVRC
     VKIFAKGTLA ISASKDYTLR LWNLLSGQEK FTIWDGGSKN PTEPQIWNLH VDEAHKVVYS
     ASGSKINAWN LETAEPVFHI LGDVSDPWMC MAVLASQATL LTVSRDGVVS LWSSATGKLQ
     GKQHMSSTKE ETPTCAVSVQ KQGKLVTGFS NGSICLVSSK GDRLLEKLPD AVRFLVVSED
     ESLLAAGSQV ISLSVAESGG FYRHRMGEGQ TVSSIGKGNI QLICPPVLLP QVWSLSEHGT
     LLDILEGVGA PVSLLARGGA LVASASPQSS SFKIWDLSNA HRSRAPAPFL DRTGLTAVSH
     NGSYVYFPKI GDKNKVTIWN LAEGEEQDSL DTSSEVRCLE VAEQRKLLFT GLVSGVVLVF
     PLNSRQDVIC IPPPEARKAV NCMSLSKCED RLAIAYDNIV LVLDITPGDP CPVIDGPRYT
     FYTQLPETLS NVAILTDYRV VYGMTNGDLF LYECANSKVF PLEAHRSRVA CVEVSHKEQL
     VVSGSEDALL CLWDLQARKW KFEMSYTSSY CRGVQCACFS KDDKYVYVGL KDRSILVWSV
     LDGTLLTVQF VHAVVNRIIP TTGGFIAPTR HGYLIREHFQ CLSARALPQD SLTNFKKAVW
     MVKSRQREEL VAAAGAPQDL ESENAQGNET KSNKCSQVCL IV
//
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