ID G1R1I3_NOMLE Unreviewed; 418 AA.
AC G1R1I3;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=SH2 domain-containing protein {ECO:0000259|PROSITE:PS50001};
GN Name=SHF {ECO:0000313|Ensembl:ENSNLEP00000007055.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000007055.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000007055.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000007055.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01034453; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01034454; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01034455; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01034456; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01034457; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01034458; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01034459; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1R1I3; -.
DR Ensembl; ENSNLET00000007404.2; ENSNLEP00000007055.1; ENSNLEG00000005822.2.
DR eggNOG; ENOG502QTRD; Eukaryota.
DR GeneTree; ENSGT00940000159452; -.
DR HOGENOM; CLU_029444_2_0_1; -.
DR InParanoid; G1R1I3; -.
DR OMA; DTNGHCE; -.
DR TreeFam; TF325799; -.
DR Proteomes; UP000001073; Chromosome 6.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR PANTHER; PTHR15127; HEAVYWEIGHT, ISOFORM A; 1.
DR PANTHER; PTHR15127:SF28; SH2 DOMAIN-CONTAINING ADAPTER PROTEIN F; 1.
DR Pfam; PF00017; SH2; 1.
DR PRINTS; PR00401; SH2DOMAIN.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50001; SH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT DOMAIN 325..413
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 1..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 113..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 227..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..50
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 187..210
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 418 AA; 46468 MW; 50E0128F3B3E2080 CRC64;
MQQDARGLVR RAPCRPETLE GSWQVSPGHR KRASPKGSLS SAQPHSWMLR PSPLNSHCPH
REPISSSSPP PVANGPKQKK KSNWRSTTRL RVIRLSSRLE PRPLAILEDY ADPFDVQETG
EGSAGASGAP EKVPENDGYM EPYEAQKMMA EIRGSKETAT QPLPLYDTPY EPEEDGATPE
GEGAPWPRES RLPEDDERPP EEYDQPWEWK KERISKAFAV DIKVIKDLPW PPPVGQLDSS
PSLPDGDRDI SGPASPLPEP SLEDSSAQFE GPEKSCLSPG REEKGRLPPR LSAGNPKSAK
PLSMEPSSPL GEWTDPALPL ENQVWYHGAI SRTDAENLLR LCREASYLVR NSETSKNDFS
LSLKSSQGFM HMKLSRTKEH KPPFSSVPEI VHHYASRKLP IKGAEHMSLL YPVAIRTL
//
