ID   G1R2Z4_NOMLE            Unreviewed;       696 AA.
AC   G1R2Z4;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 62.
DE   SubName: Full=SEC14 and spectrin domain containing 1 {ECO:0000313|Ensembl:ENSNLEP00000007566.1};
GN   Name=SESTD1 {ECO:0000313|Ensembl:ENSNLEP00000007566.1};
OS   Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC   Nomascus.
OX   NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000007566.1, ECO:0000313|Proteomes:UP000001073};
RN   [1] {ECO:0000313|Ensembl:ENSNLEP00000007566.1, ECO:0000313|Proteomes:UP000001073}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Gibbon Genome Sequencing Consortium;
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSNLEP00000007566.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the SOLO family.
CC       {ECO:0000256|ARBA:ARBA00038285}.
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DR   EMBL; ADFV01058904; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01058905; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01058906; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01058907; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01058908; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_003253835.1; XM_003253787.3.
DR   AlphaFoldDB; G1R2Z4; -.
DR   SMR; G1R2Z4; -.
DR   STRING; 61853.ENSNLEP00000007566; -.
DR   Ensembl; ENSNLET00000007935.2; ENSNLEP00000007566.1; ENSNLEG00000006220.2.
DR   eggNOG; KOG4240; Eukaryota.
DR   GeneTree; ENSGT00730000111148; -.
DR   HOGENOM; CLU_010440_1_0_1; -.
DR   InParanoid; G1R2Z4; -.
DR   OMA; PDAFWDK; -.
DR   TreeFam; TF332003; -.
DR   Proteomes; UP000001073; Chromosome 22a.
DR   GO; GO:0034704; C:calcium channel complex; IEA:Ensembl.
DR   GO; GO:0045111; C:intermediate filament cytoskeleton; IEA:Ensembl.
DR   GO; GO:0070300; F:phosphatidic acid binding; IEA:Ensembl.
DR   GO; GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IEA:Ensembl.
DR   GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IEA:Ensembl.
DR   GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IEA:Ensembl.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IEA:Ensembl.
DR   GO; GO:0070273; F:phosphatidylinositol-4-phosphate binding; IEA:Ensembl.
DR   GO; GO:0010314; F:phosphatidylinositol-5-phosphate binding; IEA:Ensembl.
DR   GO; GO:1904878; P:negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel; IEA:Ensembl.
DR   Gene3D; 1.20.58.60; -; 2.
DR   InterPro; IPR001251; CRAL-TRIO_dom.
DR   PANTHER; PTHR46607; SEC14 DOMAIN AND SPECTRIN REPEAT-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR46607:SF1; SEC14 DOMAIN AND SPECTRIN REPEAT-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF13716; CRAL_TRIO_2; 1.
DR   SUPFAM; SSF46966; Spectrin repeat; 1.
DR   PROSITE; PS50191; CRAL_TRIO; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          1..153
FT                   /note="CRAL-TRIO"
FT                   /evidence="ECO:0000259|PROSITE:PS50191"
SQ   SEQUENCE   696 AA;  79371 MW;  5C5AE08D57A7303A CRC64;
     MEASVILPIL KKKLAFLSGG KDRRSGLILT IPLCLEQTNM DELSVTLDYL LSIPSEKCKA
     RGFTVIVDGR KSQWNVVKTV VVMLQNVVPA EVSLVCVVKP DEFWDKKVTH FCFWKEKDRL
     GFEVILVSAN KLTRYIEPCQ LTEDFGGSLT YDHMDWLNKR LVFEKFTKES TSLLDELALI
     NNGSDKGNQQ EKERSVDLNF LPSVDPETVL QTGHELLSEL QQRRFNGSDG GVSWSPMDDE
     LLAQPQVMKL LDSLREQYTR YQEVCRQRSK RTQLEEIQQK VMQVVNWLEG PGSEQLRAQW
     GIGDSIRASQ ALQQKHEEIE SQHSEWFAVY VELNQQIAAL LNAGDEEDLV ELKSLQQQLS
     DVCYRQASQL EFRQNLLQAA LEFHGVAQDL SQQLDGLLGM LCVDVAPADG ASIQQTLKLL
     EEKLKSVDVG LQGLREKGQG LLDQISNQAS WAYGKDVTIE NKENVDHIQG VMEDMQLRKQ
     RCEDMVDVRR LKMLQMVQLF KCEEDAAQAV EWLSELLDAL LKTHIRLGDD AQETKVLLEK
     HRKFVDVAQS TYDYGRQLLQ ATVVLCQSLR CTSRSSGDTL PRLNRVWKQF TIASEERVHR
     LEMAIAFHSN AEKILQDCPE EPEAINDEEQ FDEIEAVGKS LLDRLTVPVV YPDGTEQYFG
     SPSDMASTAE HIRDRMKLVN LKRQQLRHPE MVTTES
//