ID   G1R4Z2_NOMLE            Unreviewed;       927 AA.
AC   G1R4Z2;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 2.
DT   27-MAR-2024, entry version 73.
DE   SubName: Full=Spliceosome associated factor 3, U4/U6 recycling protein {ECO:0000313|Ensembl:ENSNLEP00000008264.2};
GN   Name=SART3 {ECO:0000313|Ensembl:ENSNLEP00000008264.2};
OS   Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC   Nomascus.
OX   NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000008264.2, ECO:0000313|Proteomes:UP000001073};
RN   [1] {ECO:0000313|Ensembl:ENSNLEP00000008264.2, ECO:0000313|Proteomes:UP000001073}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Gibbon Genome Sequencing Consortium;
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSNLEP00000008264.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; ADFV01052930; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_003270039.1; XM_003269991.2.
DR   AlphaFoldDB; G1R4Z2; -.
DR   Ensembl; ENSNLET00000008654.2; ENSNLEP00000008264.2; ENSNLEG00000006767.3.
DR   eggNOG; KOG0128; Eukaryota.
DR   GeneTree; ENSGT00900000141107; -.
DR   HOGENOM; CLU_007172_0_0_1; -.
DR   TreeFam; TF317554; -.
DR   Proteomes; UP000001073; Chromosome 10.
DR   GO; GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   CDD; cd12391; RRM1_SART3; 1.
DR   CDD; cd12392; RRM2_SART3; 1.
DR   Gene3D; 3.30.70.330; -; 2.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR003107; HAT.
DR   InterPro; IPR008669; LSM_interact.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   InterPro; IPR034217; SART3_RRM1.
DR   InterPro; IPR034218; SART3_RRM2.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR15481; RIBONUCLEIC ACID BINDING PROTEIN S1; 1.
DR   PANTHER; PTHR15481:SF5; SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNIZED BY T-CELLS 3; 1.
DR   Pfam; PF16605; LSM_int_assoc; 1.
DR   Pfam; PF05391; Lsm_interact; 1.
DR   Pfam; PF00076; RRM_1; 2.
DR   SMART; SM00386; HAT; 6.
DR   SMART; SM00360; RRM; 2.
DR   SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50102; RRM; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW   ProRule:PRU00176}.
FT   DOMAIN          668..746
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   DOMAIN          765..842
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   REGION          1..37
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          49..86
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          554..658
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          842..862
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          885..912
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..35
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        554..569
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        640..658
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   927 AA;  105481 MW;  6B66E5E613882F41 CRC64;
     MATAAATSAS EPEAESKAGP KADGEEDEVK AARTRRKVLS RAVAAATYKT MGPGWDQQEE
     GVSESDGDEY AMASSAESSP GEYEWEYDEE EEKNQLEIER LEEQLSINVY DYNCHVDLIR
     LLRLEGELTK VRMARQKMSE IFPLTEELWL EWLHDEISMA QDGLDREHVY DLFEKAVKDY
     ICPNIWLEYG QYSVGGIGQK GGLEKVRSVF ERALSSVGLH MTKGLALWEA YREFESAIVE
     AARLEKVHSL FRRQLAIPLY DMEATFAEYE EWSEDPIPES VIQNYNKALQ QLEKYKPYEE
     ALLQAEAPRL AEYQAYIDFE MKIGDPARIQ LIFERALVEN CLVPDLWIRY SQYLDRQLKV
     KDLVLSVHNR AVRNCPWTVA LWSRYLLAME RHGVDHQVIS DSSKELEELR AAFTRALEYL
     KQEVEERFNE SGDPSCVIMQ NWARIEARLC NNMQKARELW DSIMTRGNAK YANMWLEYYN
     LERAHGDTQH CRKALHRAVQ CTSDYPEHVC EVLLTMERTE GSLEDWDVAV QKTETRLARV
     NEQRMKAAEK EAALVQQEEE KAEQRKRARA EKKALKKKKK IRGPEKRGAD EDDEKEWGDD
     EEEQPSKRRR VENSIPAAGE TQNVEVAAGP AGKCAAIDVE PPSKQKEKAA SLKRDMPKVL
     HDSSKDSITV FVSNLPYSMQ EPDVKLRPLF EACGEVVQIR PIFSNRGDFR GYCYVEFKEE
     KSALQALEMD RKSVEGRPMF VSPCVDKSKN PDFKVFRYST SLEKHKLFIS GLPFSCTKEE
     LEEICKAHGT VKDLRLVTNR AGKPKGLAYV EYENESQASQ AVMKMDGMTI KENVIKVAIS
     NPPQRKVPEK PETRKAPGGP MLLPQTYGAR GKGRTQLSLL PRALQRPGAA APQAENGPAA
     APAVATPAAT EAPKMSNADF AKLFLRK
//