ID   G1R617_NOMLE            Unreviewed;       604 AA.
AC   G1R617;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   RecName: Full=Deuterosome assembly protein 1 {ECO:0000256|ARBA:ARBA00019105};
DE   AltName: Full=Coiled-coil domain-containing protein 67 {ECO:0000256|ARBA:ARBA00030704};
GN   Name=DEUP1 {ECO:0000313|Ensembl:ENSNLEP00000008639.1};
OS   Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC   Nomascus.
OX   NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000008639.1, ECO:0000313|Proteomes:UP000001073};
RN   [1] {ECO:0000313|Ensembl:ENSNLEP00000008639.1, ECO:0000313|Proteomes:UP000001073}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Gibbon Genome Sequencing Consortium;
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSNLEP00000008639.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the CEP63 family.
CC       {ECO:0000256|ARBA:ARBA00007181}.
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DR   EMBL; ADFV01055704; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01055705; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01055706; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_003253037.1; XM_003252989.3.
DR   RefSeq; XP_012351280.1; XM_012495826.1.
DR   AlphaFoldDB; G1R617; -.
DR   STRING; 61853.ENSNLEP00000008639; -.
DR   Ensembl; ENSNLET00000009050.2; ENSNLEP00000008639.1; ENSNLEG00000007089.2.
DR   GeneID; 100588531; -.
DR   KEGG; nle:100588531; -.
DR   CTD; 159989; -.
DR   eggNOG; ENOG502QRBJ; Eukaryota.
DR   GeneTree; ENSGT00940000153190; -.
DR   HOGENOM; CLU_027471_1_0_1; -.
DR   InParanoid; G1R617; -.
DR   OMA; SHNTWEF; -.
DR   OrthoDB; 5403090at2759; -.
DR   TreeFam; TF330595; -.
DR   Proteomes; UP000001073; Chromosome 15.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0098536; C:deuterosome; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR   GO; GO:0098535; P:de novo centriole assembly involved in multi-ciliated epithelial cell differentiation; IEA:Ensembl.
DR   InterPro; IPR031470; Cep63/Deup1_N.
DR   PANTHER; PTHR18875:SF5; DEUTEROSOME ASSEMBLY PROTEIN 1; 1.
DR   PANTHER; PTHR18875; SARCOMA ANTIGEN NY-SAR-24/CYTOSKELETAL PROTEIN SOJO; 1.
DR   Pfam; PF17045; CEP63; 1.
PE   3: Inferred from homology;
KW   Cilium biogenesis/degradation {ECO:0000256|ARBA:ARBA00022794};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001073}.
FT   DOMAIN          11..280
FT                   /note="Centrosomal protein Cep63/Deup1 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF17045"
FT   COILED          86..156
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          227..275
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          345..390
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          563..601
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   604 AA;  70886 MW;  D2DF3828A0D385EA CRC64;
     MENQAHNTMG TSPCEAELQE LMEQIAIMVS NKEMDWERKV RALETRLDLR DQELANAQTC
     LDQKGQEVGL LRQKLDSLEK CNLAMTQNYE GQLQSLKAQF SKLTNNFEKL RLHQMKQNKV
     PREELPHLKE EIPFELSNLN QKLEEFRAKS REWDKQEILY QTHLISLDAQ QKLLSEKCNQ
     FQKQAQSYQT QLNGKKQCLE DSSSEIPRLI CDPDSNCEIN ERDEFIIEKL KSAVSEIALS
     RNKLQDENQK LLQELKMYQR QCQAMEAGLS EVKSELQSRD DLLRIIEMER LQLHRELLKI
     GECQNAQGNK TRLESSYLPS IKEPERKIKE PFSVMQDQPN HEKELNKIRS QLQQEEEYHN
     SEQERMRNEI SDLTEELHQK EITIATVTKK AALLEKQLKM ELEIKEKMLA KQKVSDMKYK
     VVRTENTHLK GMMGDLDPGQ YMSMDFTNRE HSRHTSINKL QYENERLRND LAKLHVNGKS
     TWTNQNTYEE TGRYAYQSQI KVEKNEERLS HDCEPNRSTT APLPPLTFQA KEMTSPLVSD
     DEVFPLSPPD MSFPASLAAQ HFLLEEEKRA KELEKLLNTH IDELQRHTEF TLNNYSKLKQ
     NRHI
//