ID G1R6Q8_NOMLE Unreviewed; 55 AA.
AC G1R6Q8;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=Spermatid nuclear transition protein 1 {ECO:0000256|ARBA:ARBA00015111};
GN Name=TNP1 {ECO:0000313|Ensembl:ENSNLEP00000008880.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000008880.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000008880.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000008880.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the nuclear transition protein 1 family.
CC {ECO:0000256|ARBA:ARBA00005481}.
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DR EMBL; ADFV01110657; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003254107.1; XM_003254059.2.
DR AlphaFoldDB; G1R6Q8; -.
DR STRING; 61853.ENSNLEP00000008880; -.
DR Ensembl; ENSNLET00000009300.2; ENSNLEP00000008880.1; ENSNLEG00000007281.2.
DR GeneID; 100579297; -.
DR KEGG; nle:100579297; -.
DR CTD; 7141; -.
DR eggNOG; ENOG502TKT1; Eukaryota.
DR GeneTree; ENSGT00390000000539; -.
DR HOGENOM; CLU_3019482_0_0_1; -.
DR InParanoid; G1R6Q8; -.
DR OMA; FKSHGMR; -.
DR TreeFam; TF338391; -.
DR Proteomes; UP000001073; Chromosome 22a.
DR GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030317; P:flagellated sperm motility; IEA:Ensembl.
DR GO; GO:0031507; P:heterochromatin formation; IEA:Ensembl.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:Ensembl.
DR GO; GO:0006337; P:nucleosome disassembly; IEA:Ensembl.
DR GO; GO:0010954; P:positive regulation of protein processing; IEA:Ensembl.
DR GO; GO:0000012; P:single strand break repair; IEA:Ensembl.
DR GO; GO:0035092; P:sperm DNA condensation; IEA:Ensembl.
DR GO; GO:0007290; P:spermatid nucleus elongation; IEA:Ensembl.
DR InterPro; IPR001319; Nuclear_transition_prot1.
DR InterPro; IPR020062; Nuclear_transition_prot1_CS.
DR PANTHER; PTHR17486; SPERMATID NUCLEAR TRANSITION PROTEIN 1; 1.
DR PANTHER; PTHR17486:SF0; SPERMATID NUCLEAR TRANSITION PROTEIN 1; 1.
DR Pfam; PF02079; TP1; 1.
DR PROSITE; PS00541; TP1; 1.
PE 3: Inferred from homology;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleosome core {ECO:0000256|ARBA:ARBA00023269};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Spermatogenesis {ECO:0000256|ARBA:ARBA00022871}.
FT REGION 1..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..38
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..55
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 55 AA; 6424 MW; E29C58EB2AADF3BB CRC64;
MSTSRKLKSH GMRRSKSRSP HKGVKRGGSK RKYRKGNLKS RKRGDDANRN YRSHL
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