ID G1R8W4_NOMLE Unreviewed; 1283 AA.
AC G1R8W4;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Sperm associated antigen 9 {ECO:0000313|Ensembl:ENSNLEP00000009651.2};
GN Name=SPAG9 {ECO:0000313|Ensembl:ENSNLEP00000009651.2};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000009651.2, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000009651.2, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000009651.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the JIP scaffold family.
CC {ECO:0000256|ARBA:ARBA00009866}.
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DR EMBL; ADFV01070135; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01070136; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01070137; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01070138; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01070139; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01070140; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01070141; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01070142; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01070143; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01070144; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Ensembl; ENSNLET00000010113.2; ENSNLEP00000009651.2; ENSNLEG00000007894.3.
DR eggNOG; KOG2077; Eukaryota.
DR GeneTree; ENSGT00940000153496; -.
DR HOGENOM; CLU_003841_0_0_1; -.
DR TreeFam; TF313096; -.
DR Proteomes; UP000001073; Chromosome 14.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005078; F:MAP-kinase scaffold activity; IEA:InterPro.
DR Gene3D; 1.20.58.1770; -; 1.
DR Gene3D; 1.20.5.1000; arf6 gtpase in complex with a specific effector, jip4; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR039911; JIP3/JIP4.
DR InterPro; IPR032486; JIP_LZII.
DR InterPro; IPR019143; JNK/Rab-associated_protein-1_N.
DR InterPro; IPR034743; RH1.
DR InterPro; IPR034744; RH2.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR13886:SF2; C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 4; 1.
DR PANTHER; PTHR13886; JNK/SAPK-ASSOCIATED PROTEIN; 1.
DR Pfam; PF16471; JIP_LZII; 1.
DR Pfam; PF09744; Jnk-SapK_ap_N; 2.
DR Pfam; PF19056; WD40_2; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS51776; RH1; 1.
DR PROSITE; PS51777; RH2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073}.
FT DOMAIN 7..105
FT /note="RH1"
FT /evidence="ECO:0000259|PROSITE:PS51776"
FT DOMAIN 471..542
FT /note="RH2"
FT /evidence="ECO:0000259|PROSITE:PS51777"
FT REGION 153..268
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 444..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 534..571
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1201..1228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 78..133
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 698..725
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 202..226
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..260
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 550..571
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1283 AA; 141596 MW; 50808BE2DC7A700D CRC64;
MELEDGVVYQ EEPGGSGAVM SERVSGLAGS IYREFERLIG RYDEEVVKEL MPLVVAVLEN
LDSVFAQDQE HQKFIEFEDS QEQEKKDLQT RVESLESQTR QLELKAKNYA DQISRLEERE
AELKKEYNAL HQRHTEMIHN YMEHLERTKL HQLSGSDQLE STAHSRIRKE RPISLGIFPL
PAGDGMLTPD AQKGGETPGS EQWKFQELSQ PRSHTSLKVS NSPEPQKAVE QEDELSDVSQ
GGSKATTPAS TANSDVATIP TDTPLKEENE GFVKVTDAPN KSEISKHIEV QVAQETRNVS
TGSAENEEKS EVQAIIESTP ELDMDKDLSG YKGSSTPTKG IENKAFDRNT ESLFEELSSA
GSGLIGDVDE GADLLGMGRE VENLILENTQ LLETKNALNI VKNDLIAKVD ELTCEKDVLQ
GELEAVKQAK LKLEEKNREL EEELRKARAE AEDARQKAKD DDDSDIPTAQ RKRFTRVEMA
RVLMERNQYK ERLMELQEAV RWTEMIRASR ENPAMQEKKR SSIWQFFSRL FSSSSNTTKK
PEPPVNLKYN APTSHVTPSV KKRSSTLSQL PGDKSKAFDF LSEETEASLA SRREQKREQY
RQVKAHVQKE DGRVQAFGWS LPQKYKQVTN GQGENKMKNL PVPVYLRPLD EKDTSMKLWC
AVGVNVSGGK TRDGGSVVGA SVFYKDVAGF DPEGSKQRSA SQSSLDKLDQ ELKEQQKELK
NQEELSSLVW ICTSTHSATK VLIIDAVQPG NILDSFTVCN SHVLCIASVP GARETDYPAG
EDLSESGQVD KASLCGSMTS NSSAETDSLL GGITVVGCSA EGVTGAATSP STNGASPVMD
KPPGISILFT SEEATEATEG NAGSAEDTVD VTQTGVYTEH VFTDPLGVQI PEDLSPVYQS
SNDSDAYKDQ ISVLPNEQDL VREEAQKMSS LLPTMWLGAQ NVCMSISSVA QWRKCLHSIK
LKDSILSIVH VKGIVLVALA DGTLAIFHRG VDGQWDLSNY HLLDLGRPHH SIRCMTVVHD
KVWCGYRNKI YVVQPKAMKI EKSFDAHPRK ESQVRQLAWV GDGVWVSIRL DSTLRLYHAH
TYQHLQDVDI EPYVSKMLGT GKLGFSFVRI TALMVSCNRL WVGTGNGVII SIPLTETNKT
SGVPGNRPGS VIRVYGDENS DKVTPGTFIP YCSMAHAQLC FHGHRDAVKF FVAVPGQVIS
PQSSSSGTDL TGDKAGPSAQ EPGSQTPLKS MLVISGGEGY IDFRMGDEGG ESELLGEDLP
LEPSVTKAER SHLIVWQVMY GSE
//
