ID G1RD02_NOMLE Unreviewed; 528 AA.
AC G1RD02;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 2.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=EBF family member 4 {ECO:0000313|Ensembl:ENSNLEP00000011101.2};
GN Name=EBF4 {ECO:0000313|Ensembl:ENSNLEP00000011101.2};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000011101.2, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000011101.2, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000011101.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU004489}.
CC -!- SIMILARITY: Belongs to the COE family. {ECO:0000256|ARBA:ARBA00010340,
CC ECO:0000256|RuleBase:RU004489}.
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DR EMBL; ADFV01076789; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01076790; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01076791; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012367266.1; XM_012511812.1.
DR AlphaFoldDB; G1RD02; -.
DR Ensembl; ENSNLET00000011649.2; ENSNLEP00000011101.2; ENSNLEG00000009110.2.
DR GeneID; 100589539; -.
DR KEGG; nle:100589539; -.
DR CTD; 57593; -.
DR eggNOG; KOG3836; Eukaryota.
DR GeneTree; ENSGT00950000182859; -.
DR HOGENOM; CLU_016320_3_1_1; -.
DR OrthoDB; 3641706at2759; -.
DR TreeFam; TF313391; -.
DR Proteomes; UP000001073; Chromosome 13.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd11606; COE_DBD; 1.
DR CDD; cd01175; IPT_COE; 1.
DR Gene3D; 1.10.287.4280; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.40.3180; Transcription factor COE1, DNA-binding domain; 1.
DR InterPro; IPR032200; COE_DBD.
DR InterPro; IPR038173; COE_DBD_sf.
DR InterPro; IPR032201; COE_HLH.
DR InterPro; IPR038006; COE_IPT.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR003523; Transcription_factor_COE.
DR InterPro; IPR018350; Transcription_factor_COE_CS.
DR PANTHER; PTHR10747; TRANSCRIPTION FACTOR COE FAMILY MEMBER; 1.
DR PANTHER; PTHR10747:SF36; TRANSCRIPTION FACTOR COE4; 1.
DR Pfam; PF16422; COE1_DBD; 1.
DR Pfam; PF16423; COE1_HLH; 1.
DR Pfam; PF01833; TIG; 1.
DR SMART; SM00429; IPT; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR PROSITE; PS01345; COE; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|RuleBase:RU004489};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004489};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU004489};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU004489};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004489};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU004489};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004489};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|RuleBase:RU004489}.
FT DOMAIN 181..265
FT /note="IPT/TIG"
FT /evidence="ECO:0000259|SMART:SM00429"
FT REGION 374..402
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 484..528
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 386..402
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 528 AA; 56601 MW; 411DC48E6D6D1F86 CRC64;
MYDRQGQPVE VERTAFIDFV EKDREPGAEK TNNGIHYRLR LVYNNGLRTE QDLYVRLIDS
MSKQAIIYEG QDKNPEMCRV LLTHEIMCSR CCDRKSCGNR NETPSDPVII DRFFLKFFLK
CNQNCLKNAG NPRDMRRFQV VVSTTVSVDG HVLAVSDNMF VHNNSKHGRR ARRLDPSEAA
TPCIKAISPG EGWTTGGATV IVIGDNFFDG LQVVFGNVLV WSELITPHAI RVQTPPRHIP
GVVEVTLSYK SKQFCKGSPG RFVYTALNEP TIDYGFQRLQ KVIPRHPGDP ERLPKEVLLK
RAADLAEALY GVPGSNQELL LKRAADVAEA LYSTPRAPGP LGPLAPSHPH PAVVGINAFS
SPLAIAVGDA TPGPEPGYAR SCSSASPRGF APSPGSQQSG YGSGLGAGLG GYGAPGVAGL
GVPGSPSFLN GSTATSPFAI MPSSPPLAAA SSMSLPAAAP TTSIFSFSPV NMISAVKQRS
AFAPVLRPPS SPPQACPRAH GEGLPDQSFE DSDKFHSPAR GLQGLAYS
//
