ID G1RSB5_NOMLE Unreviewed; 857 AA.
AC G1RSB5;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Semaphorin 6B {ECO:0000313|Ensembl:ENSNLEP00000016137.2};
GN Name=SEMA6B {ECO:0000313|Ensembl:ENSNLEP00000016137.2};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000016137.2, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000016137.2, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000016137.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR EMBL; ADFV01125207; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01125208; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01125209; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01125210; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01125211; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1RSB5; -.
DR STRING; 61853.ENSNLEP00000016137; -.
DR Ensembl; ENSNLET00000016960.2; ENSNLEP00000016137.2; ENSNLEG00000013327.2.
DR eggNOG; KOG3611; Eukaryota.
DR GeneTree; ENSGT00940000159170; -.
DR HOGENOM; CLU_009051_2_1_1; -.
DR InParanoid; G1RSB5; -.
DR OMA; AYMSQQH; -.
DR TreeFam; TF316102; -.
DR Proteomes; UP000001073; Chromosome 17.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:Ensembl.
DR GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF10; SEMAPHORIN-6B; 1.
DR Pfam; PF01437; PSI; 1.
DR Pfam; PF01403; Sema; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..857
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014175681"
FT TRANSMEM 584..604
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 31..503
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT REGION 631..658
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 675..722
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 759..857
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 694..708
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 797..819
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 857 AA; 92078 MW; 30F406B36296AB96 CRC64;
MQTPRASPPR PALLLLLLLL GGAHGLFPEE PPPLSVAPRD YLNHYPVFVG SGPGRLTPAE
GADDLNIQRV LRVNRTLFIG DRDNLYRVEL EPPTSTELRY QRKLTWRSNP SDINVCRMKG
KQEGECRNFV KVLLLRDEST LFVCGSNAFN PVCANYSIDT LQPVGDNISG MARCPYDPKH
ANVALFSDGM LFTATVTDFL AIDAVIYRSL GDRPTLRTVK HDSKWFKEPY FVHAVEWGSH
VYFFFREIAM EFNYLEKVVV SRVARVCKND VGGSPRVLEK QWTSFLKARL NCSAVTGVLL
HPIKICVFKN IPGSAVCAFD MTQVAAVFEG RFREQKSPES IWTPVPEDQV PRPRPGCCAA
PGMQYNASSA LPDDILNFVK THPLMDEAVP SLGHAPWIVR TLMRHQLTRV AVDVGAGPWG
NQTVVFLGSE AGTVLKFLVR PNASTSGTSG LSVFLEEFET YRPDRCGRPG GGETGQRLLS
LELDAASGGL LAAFPRCVVR VPVARCQQYS GCMKNCIGSQ DPYCGWAPDG VCIFLSPGTR
AAFEQDVSGA STSGLGDCTG LLRASLSEDR AGLVSVNLLV TSSVAAFVVG AVVSGFSVGW
FMGLRERREL ARRKDKEAIL AHGAGEAVLS VSRLGERRAQ GPGGRSGGGG GGAGVPPEAL
LAPLMQNGWA KATLLQGGPH DLDSGLLPTP EQTPLPQKRL PTPHPHPHAL GPRAWDHGHP
LLPASASSSL LLLAPARAPE QPPAPGEPTP DARLYAARPG RASHGDFPLT PHASPDRRRV
VSAPTGPLDP ASAADGLPRP WSPPPTGSLR RPPGPHAPPA ATLRRTHTFN SGGARPGTDL
AHLLPYGGAD RTAPPVP
//
