ID G1RXE1_NOMLE Unreviewed; 538 AA.
AC G1RXE1;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Kelch like family member 7 {ECO:0000313|Ensembl:ENSNLEP00000017918.2};
GN Name=KLHL7 {ECO:0000313|Ensembl:ENSNLEP00000017918.2};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000017918.2, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000017918.2, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000017918.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01060224; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01060225; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01060226; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01060227; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003270439.1; XM_003270391.3.
DR AlphaFoldDB; G1RXE1; -.
DR SMR; G1RXE1; -.
DR STRING; 61853.ENSNLEP00000017918; -.
DR Ensembl; ENSNLET00000018811.2; ENSNLEP00000017918.2; ENSNLEG00000014714.3.
DR GeneID; 100599716; -.
DR CTD; 55975; -.
DR eggNOG; KOG4441; Eukaryota.
DR GeneTree; ENSGT00940000155602; -.
DR HOGENOM; CLU_004253_14_2_1; -.
DR InParanoid; G1RXE1; -.
DR OMA; WRAASPM; -.
DR OrthoDB; 5472491at2759; -.
DR TreeFam; TF351653; -.
DR Proteomes; UP000001073; Chromosome 17.
DR GO; GO:0031463; C:Cul3-RING ubiquitin ligase complex; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR GO; GO:0016567; P:protein ubiquitination; IEA:Ensembl.
DR CDD; cd18447; BACK_KLHL7; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR047060; KLHL7_BACK.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR45632; LD33804P; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 3.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 4.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1..63
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 538 AA; 60725 MW; 8B7ABA54C28D56C1 CRC64;
MVQERKIPAH RVVLAAASHF FNLMFTTNML ESKSFEVELK DAEPDIIEQL VEFAYTARIS
VNSNNVQSLL DAANQYQIEP VKKMCVDFLK EQVDASNCLG ISVLAECLDC PELKATADDF
IHQHFTEVYK TDEFLQLDVK RVTHLLNQDT LTVRAEDQVY DAAVRWLKYD EPNRQPFMVD
ILAKVRFPLI SKNFLSKTVQ AEPLIQDNPE CLKMVISGMR YHLLSPEDRE ELVDGTRPRR
KKHDYRIALF GGSQPQSCRY FNPKDYSWTD IRCPFEKRRD AACVFWDNVV YILGGSQLFP
IKRMDCYNVV KDSWYSKLGP PTPRDSLAAC AAEGKIYTSG GSEVGNSALY LFECYDTRTE
SWHTKPSMLT QRCSHGMVEA NGLIYVCGGS LGNNVSGRVL NSCEVYDPAT ETWTELCPMI
EARKNHGLVF VKDKIFAVGG QNGLGGLDNV EYYDIKLNEW KMVSPMPWKG VTVKCAAVGS
IVYVLAGFQG VGRLGHILEY NTETDKWVAN SKVRAFPVTS CLICVVDTCG ANEETLET
//
