ID   G1RYM1_NOMLE            Unreviewed;        79 AA.
AC   G1RYM1;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   RecName: Full=Beta-defensin 130 {ECO:0008006|Google:ProtNLM};
GN   Name=DEFB130B {ECO:0000313|Ensembl:ENSNLEP00000018348.1};
OS   Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC   Nomascus.
OX   NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000018348.1, ECO:0000313|Proteomes:UP000001073};
RN   [1] {ECO:0000313|Ensembl:ENSNLEP00000018348.1, ECO:0000313|Proteomes:UP000001073}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Gibbon Genome Sequencing Consortium;
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSNLEP00000018348.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR   EMBL; ADFV01065874; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_003271499.1; XM_003271451.1.
DR   AlphaFoldDB; G1RYM1; -.
DR   STRING; 61853.ENSNLEP00000018348; -.
DR   Ensembl; ENSNLET00000019259.2; ENSNLEP00000018348.1; ENSNLEG00000015099.2.
DR   GeneID; 100606142; -.
DR   KEGG; nle:100606142; -.
DR   CTD; 100133267; -.
DR   eggNOG; ENOG502TEXC; Eukaryota.
DR   GeneTree; ENSGT00940000160995; -.
DR   HOGENOM; CLU_191088_0_0_1; -.
DR   InParanoid; G1RYM1; -.
DR   OMA; TIGVCND; -.
DR   OrthoDB; 4640037at2759; -.
DR   Proteomes; UP000001073; Chromosome 4.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   InterPro; IPR001855; Defensin_beta-typ.
DR   PANTHER; PTHR20515; BETA-DEFENSIN; 1.
DR   PANTHER; PTHR20515:SF1; BETA-DEFENSIN 130A-RELATED; 1.
DR   Pfam; PF00711; Defensin_beta; 1.
DR   SUPFAM; SSF57392; Defensin-like; 1.
PE   4: Predicted;
KW   Antibiotic {ECO:0000256|ARBA:ARBA00023022};
KW   Antimicrobial {ECO:0000256|ARBA:ARBA00022529};
KW   Defensin {ECO:0000256|ARBA:ARBA00022940};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..79
FT                   /note="Beta-defensin 130"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003421255"
SQ   SEQUENCE   79 AA;  8823 MW;  95FD21F83C62D504 CRC64;
     MKLHSLISVL LLFVTLIPKG KTGVIPGQKQ CIALKGVCRD KLCSTLDDTI GKCNEEKKCC
     RRWWILEPYP TPVPKGKSP
//