ID G1RZY2_NOMLE Unreviewed; 783 AA.
AC G1RZY2;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=BMP/retinoic acid inducible neural specific 2 {ECO:0000313|Ensembl:ENSNLEP00000018810.1};
GN Name=BRINP2 {ECO:0000313|Ensembl:ENSNLEP00000018810.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000018810.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000018810.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000018810.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the BRINP family.
CC {ECO:0000256|ARBA:ARBA00010360}.
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DR EMBL; ADFV01184842; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01184843; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01184844; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003258981.1; XM_003258933.2.
DR RefSeq; XP_012366449.1; XM_012510995.1.
DR AlphaFoldDB; G1RZY2; -.
DR STRING; 61853.ENSNLEP00000018810; -.
DR Ensembl; ENSNLET00000019755.2; ENSNLEP00000018810.1; ENSNLEG00000015495.2.
DR GeneID; 100584221; -.
DR KEGG; nle:100584221; -.
DR CTD; 57795; -.
DR eggNOG; ENOG502QQZS; Eukaryota.
DR GeneTree; ENSGT00940000160314; -.
DR HOGENOM; CLU_018347_0_0_1; -.
DR InParanoid; G1RZY2; -.
DR OMA; LSACCRW; -.
DR OrthoDB; 3949486at2759; -.
DR TreeFam; TF331600; -.
DR Proteomes; UP000001073; Chromosome 12.
DR GO; GO:0071300; P:cellular response to retinoic acid; IEA:Ensembl.
DR GO; GO:0021953; P:central nervous system neuron differentiation; IEA:Ensembl.
DR GO; GO:0045930; P:negative regulation of mitotic cell cycle; IEA:Ensembl.
DR GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:InterPro.
DR InterPro; IPR033237; BRINP.
DR InterPro; IPR020864; MACPF.
DR PANTHER; PTHR15564:SF8; BMP_RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 2; 1.
DR PANTHER; PTHR15564; MACPF DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF19052; BRINP; 1.
DR Pfam; PF01823; MACPF; 1.
DR SMART; SM00457; MACPF; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00022810};
KW Growth arrest {ECO:0000256|ARBA:ARBA00022810};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..33
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 34..783
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003421296"
FT DOMAIN 89..281
FT /note="MACPF"
FT /evidence="ECO:0000259|SMART:SM00457"
SQ SEQUENCE 783 AA; 89022 MW; E26DC96E0722BCBF CRC64;
MRWQCGTRFR GLRPAVAPWT ALLALGLPGW VLAVSATAAA VVPEQHASVA GQHPLDWLLT
DRGPFHRAQE YADFMERYRQ GFTTRYRIYR EFARWKVNNL ALERKDFFSL PLPLAPEFIR
NIRLLGRRPN LQQVTENLIK KYGTHFLLSA TLGGEESLTI FVDKRKLGRK TETTGGASII
GGSGNSTAVS LETLHQLAAS YFIDRESTLR RLHHIQIATG AIKVTETRTG PLGCSNYDNL
DSVSSVLVQS PENKVQLLGL QVLLPEYLRE RFVAAALSYI TCSSEGELVC KENDCWCKCS
PSFPECNCPD ADIQAMEDSL LQIQDSWATH NRQFEESEEF QTLLKRLPDD RFLNSTAISQ
FWAMDTSLQH RYQQLGAGLK VLFKKTHRIV RRLFNLCKRC HRQPRFRLPK ERSLSYWWNR
IQSLLYCGES TFPGTFLEQS HSCTCPYDQS SCQGPIPCAL GEGPACAHCA PDNSTRCGSC
NPGYVLAQGL CRPEVAESLE NFLGLETDLQ DLELKYLLQK QDSRIEVHSI FISNDMRLGS
WFDPSWRKRM LLTLKSNKYK PGLVHVMLAL SLQICLTKNS TLEPVMAIYV NPFGGSHSES
WFMPVNEGSF PEWERTNVDA AAQCQNWTIT LGNRWKTFFE TVHVYLRSRI KSLDDSSNET
IYYEPLEMTD PSKNLGYMKI NTLQVFGYSL PFDPDAIRDL ILQLDYPYTQ GSQDSALLQL
IELRDRVNQL SPPGKVRLDL FSCLLRHRLK LASNEVGRIQ SSLRAFNSKL PNPVEYETGK
LCS
//
