ID G1RZY3_NOMLE Unreviewed; 475 AA.
AC G1RZY3;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=CNKSR family member 3 {ECO:0000313|Ensembl:ENSNLEP00000018811.2};
GN Name=CNKSR3 {ECO:0000313|Ensembl:ENSNLEP00000018811.2};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000018811.2, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000018811.2, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000018811.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01166800; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01166801; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01166802; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01166803; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01166804; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01166805; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012361583.1; XM_012506129.1.
DR AlphaFoldDB; G1RZY3; -.
DR Ensembl; ENSNLET00000019756.3; ENSNLEP00000018811.2; ENSNLEG00000015493.3.
DR eggNOG; KOG1738; Eukaryota.
DR GeneTree; ENSGT00940000154428; -.
DR HOGENOM; CLU_037920_0_0_1; -.
DR OMA; MEPVTRW; -.
DR TreeFam; TF326495; -.
DR Proteomes; UP000001073; Chromosome 3.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0009966; P:regulation of signal transduction; IEA:InterPro.
DR Gene3D; 2.30.42.10; -; 1.
DR InterPro; IPR010599; CNK2/3_dom.
DR InterPro; IPR017874; CRIC_domain.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR12844; CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS; 1.
DR PANTHER; PTHR12844:SF17; CONNECTOR ENHANCER OF KINASE SUPPRESSOR OF RAS 3; 1.
DR Pfam; PF06663; CNK2_3_dom; 1.
DR Pfam; PF10534; CRIC_ras_sig; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS51290; CRIC; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001073}.
FT DOMAIN 1..94
FT /note="CRIC"
FT /evidence="ECO:0000259|PROSITE:PS51290"
FT DOMAIN 131..213
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 229..254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 267..310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 437..457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 475 AA; 52662 MW; F83AC046BFF2D794 CRC64;
MKNLVLKLRA SSHNLQNYIS SRRKSPAYDG NTSRKAPNEF LTSVVELIGA AKALLAWLDR
APFTGITDFS VTKNKIIQLC LDLTTTVQKD CCVAEMEDKV LTVVKVLNGI CDKTIRSTTD
PVMSQCACLE EVHLPNIKPG EGLGMYIKST YDGLHVITGT TENSPADRSQ KIHAGDEVIQ
VNQQTVVGWQ LKNLVKKLRE NPTGVVLLLK KRPTGSFNFT PAPLKNLRWK PPLVQTSPPP
TTTQSPESTM DTSLKKEKSA ILDLYIPPPP AVPYSPRDEN GSFVYGGSSK YKQPLPGPKG
SESPNSFLDQ ESRRRRFTIA DSDQLPGYSA ETNILPTKMR EKTPSYGKPR PLSMPADGNW
MGIVDPFARP RGHGRKGEDA LCRYFSNERI PPIIEESSSP PYRFSRPTTE RHLVRGADYI
RGSRCYINSD LHSSATIPFQ EEGTKKKSGS SATKSSSTEP SLLVSWFTRL KLLTH
//
