ID G1S2F7_NOMLE Unreviewed; 1077 AA.
AC G1S2F7;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Tudor domain containing 1 {ECO:0000313|Ensembl:ENSNLEP00000019695.2};
GN Name=TDRD1 {ECO:0000313|Ensembl:ENSNLEP00000019695.2};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000019695.2, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000019695.2, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000019695.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01164157; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01164158; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01164159; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01164160; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01164161; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01164162; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01164163; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1S2F7; -.
DR Ensembl; ENSNLET00000020687.2; ENSNLEP00000019695.2; ENSNLEG00000016228.2.
DR GeneTree; ENSGT00940000158754; -.
DR Proteomes; UP000001073; Chromosome 3.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd20408; Tudor_TDRD1_rpt1; 1.
DR CDD; cd20409; Tudor_TDRD1_rpt2; 1.
DR CDD; cd20410; Tudor_TDRD1_rpt3; 1.
DR CDD; cd20411; Tudor_TDRD1_rpt4; 1.
DR Gene3D; 2.30.30.140; -; 4.
DR Gene3D; 2.40.50.90; -; 4.
DR Gene3D; 6.10.140.2220; -; 1.
DR InterPro; IPR035437; SNase_OB-fold_sf.
DR InterPro; IPR002999; Tudor.
DR InterPro; IPR047376; Tudor_TDRD1_rpt1.
DR InterPro; IPR047377; Tudor_TDRD1_rpt2.
DR InterPro; IPR047378; Tudor_TDRD1_rpt3.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR22948; TUDOR DOMAIN CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22948:SF29; TUDOR DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00567; TUDOR; 4.
DR Pfam; PF01753; zf-MYND; 1.
DR SMART; SM00333; TUDOR; 4.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 4.
DR PROSITE; PS50304; TUDOR; 4.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 4: Predicted;
KW Differentiation {ECO:0000256|ARBA:ARBA00022871};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Spermatogenesis {ECO:0000256|ARBA:ARBA00022871};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT DOMAIN 170..206
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT DOMAIN 312..372
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT DOMAIN 541..600
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT DOMAIN 762..821
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT DOMAIN 954..1012
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT REGION 1..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 79..139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 450..469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..66
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..94
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 112..134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 453..467
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1077 AA; 120871 MW; 113E9E1847FA92C3 CRC64;
MSVKSPFNIM SRNNLEAPPC KMTEPFNFEK NENKLPPHES LRSPGTLPNH PNFRLKSSEN
GNKKNNFLLC EQTKQYLASQ EDNSVSSNPN GINGEVVGSK GDRKKLPAGN SVSPLSAESN
SPPKEVNTKP GNNVPPAKSK KLNKLVENSL SINNPGLFTS LGPPLRSTTC HRCGLFGSMR
CSQCKQTYYC STACQRRDWS AHSIVCKPVQ PNFHKLDNKS SIETKDVEVN NKSDCPLGVT
KEIAIWAERI MFSDLRSLQL KKTMEIKGTV TEFKHPGDFH VQLYSSEVLE YMNQLSVSLK
ETYANMHEKD YIPVKGEVCI AKYTVDQTWN RAIIQNVDVQ QKKAHVLYID YGNEEIIPLN
RIYHLNRNID LFPPCAIKCF VANVIAAEGN WSNDCIKATK PLLMEQYCSI KIVDILEEEV
VTFAVEVELP NSGKLLDHVL IEMGYGLKPN GQDSKKENAD QSDPEDVGKM TTENNIVVDK
SDLIPKVLTL NVGDEFCGVV AHIQTPEDFF CQQLQSGRKL AELQASLSKY CGQLPPRSDF
YPAIGDICCA RFSEDDQWYR ASVLAYASEE SVLVGYVDYG NFEILSLMRL CPIIPKLLEL
PMQAIKCVLA GVKPSLGIWT PEAICLMKKL VQNRIITVKV VDKLENSSLV ELIDKSETPD
VSVSRVLVDA GFAVGEQSMV TDKPSDVKET SVPLGVEGKV NPLEWTWVEL AVDQTVDVVV
CVIYSPGEFY CHVLKEDALK KLNDLNKSLA EHCQQKLPIG FKAEIGQPCC AFFAGDGNWY
RALIKEILPN GHVKVHFVDY GNIEEVTADE LRMIPSTFLN LPFQGIRCQL ADIQYSNKHW
SEEATTRFHM CVDGIKLQAR GIPPHWNLPN DRLVNKHELQ VHVQGLQATS SAEQWKTIEL
PVNKTIQANV LEIISPNLFY ALPKGMPENQ EKLCMLTAEL LEYCNAPKSR PPYRPRIGDA
CCAKYTSDDF WYRAVVLGTS DTDVEVLYAD YGNIETLPLC RVQPITSSQL ALPFQIIRCS
LEEKRYRMNC CCAELQKQVE KHEHILLFLL NNSTNQNKFI EMKKLLKTTA SLGGKPL
//
