ID G1S618_NOMLE Unreviewed; 542 AA.
AC G1S618;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=STAS domain-containing protein {ECO:0000259|PROSITE:PS50801};
GN Name=SLC26A10P {ECO:0000313|Ensembl:ENSNLEP00000020956.2};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000020956.2, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000020956.2, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000020956.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362052}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362052}.
CC -!- SIMILARITY: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
CC {ECO:0000256|ARBA:ARBA00008692, ECO:0000256|RuleBase:RU362052}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362052}.
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DR EMBL; ADFV01002275; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01002276; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01002277; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1S618; -.
DR Ensembl; ENSNLET00000022009.2; ENSNLEP00000020956.2; ENSNLEG00000017254.2.
DR eggNOG; KOG0236; Eukaryota.
DR GeneTree; ENSGT01070000253775; -.
DR HOGENOM; CLU_003182_9_4_1; -.
DR TreeFam; TF313784; -.
DR Proteomes; UP000001073; Chromosome 11.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008509; F:monoatomic anion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0098661; P:inorganic anion transmembrane transport; IEA:UniProtKB-UniRule.
DR CDD; cd07042; STAS_SulP_like_sulfate_transporter; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR011547; SLC26A/SulP_dom.
DR InterPro; IPR001902; SLC26A/SulP_fam.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR PANTHER; PTHR11814:SF99; SOLUTE CARRIER FAMILY 26 MEMBER 10; 1.
DR PANTHER; PTHR11814; SULFATE TRANSPORTER; 1.
DR Pfam; PF01740; STAS; 1.
DR Pfam; PF00916; Sulfate_transp; 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS50801; STAS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362052};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362052};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362052}; Transport {ECO:0000256|RuleBase:RU362052}.
FT TRANSMEM 44..69
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 116..140
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 277..300
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 320..342
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 349..372
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT DOMAIN 403..520
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
SQ SEQUENCE 542 AA; 57565 MW; AFA26FD96C828CEC CRC64;
MRHDLASLMP APKSLGSAFK SWRLDKAPSP QHTFPSTSIP GMAFALLASV PPVFGLYTSF
FPVLIYSLLG TGRHLSTGTF AILSLMTGSA VERLVPEPLV GNLSGIEKEQ LDAQRVGVAA
AMAFGSGALM LGMFVLQLGV LSTFLSEPVV KALTSGAALH VFVSQLPSLL GLSSRARSTL
AAVLTALPPS SPAELTISAL SLELLVPVKE LNVRFRDRLL TPIPGEVVLV RMAVRASGLL
LCFTSSLDTR YHVQIVGLLP GGFPQPLLPN LAELPRILAD LLPIALVTVV VSASLASIYA
DKYSYTIDSN QLLAHGASNL ISSLFSCFPN SATLATTSLL VDAGGKTQLA GLFSCIVVLS
VLLWLGPFFY YLPKAVLACI NISSMRQMFC QMQELPQLCY PTPLYFETCG QFRCNLEWHL
GLGEGEKETS KPDGPTVAVA EPVRVVVLDF SGVTFADAAG AREVVEVRER LASQCRDARI
RLLLAQCNAS VLGTLTRAGL LDRVTPDQLF VSVQDAAAYA LGSLVRGSSA RSGSQEALGC
GK
//
