ID G1S6L5_NOMLE Unreviewed; 818 AA.
AC G1S6L5;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Erythrocyte membrane protein band 4.1 like 4B {ECO:0000313|Ensembl:ENSNLEP00000021154.2};
GN Name=EPB41L4B {ECO:0000313|Ensembl:ENSNLEP00000021154.2};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000021154.2, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000021154.2, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000021154.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01191117; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01191118; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01191119; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01191120; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01191121; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01191122; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01191123; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01191124; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01191125; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01191126; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1S6L5; -.
DR STRING; 61853.ENSNLEP00000021154; -.
DR Ensembl; ENSNLET00000022229.2; ENSNLEP00000021154.2; ENSNLEG00000017431.2.
DR eggNOG; KOG3530; Eukaryota.
DR GeneTree; ENSGT00940000158331; -.
DR InParanoid; G1S6L5; -.
DR TreeFam; TF319780; -.
DR Proteomes; UP000001073; Chromosome 1a.
DR GO; GO:0045177; C:apical part of cell; IEA:Ensembl.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.
DR GO; GO:0031032; P:actomyosin structure organization; IEA:Ensembl.
DR GO; GO:0045785; P:positive regulation of cell adhesion; IEA:Ensembl.
DR GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR GO; GO:0051549; P:positive regulation of keratinocyte migration; IEA:Ensembl.
DR GO; GO:0042060; P:wound healing; IEA:Ensembl.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13186; FERM_C_NBL4_NBL5; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR000798; Ez/rad/moesin-like.
DR InterPro; IPR014847; FA.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR PANTHER; PTHR23280:SF18; BAND 4.1-LIKE PROTEIN 4B; 1.
DR Pfam; PF08736; FA; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR PRINTS; PR00935; BAND41.
DR PRINTS; PR00661; ERMFAMILY.
DR SMART; SM00295; B41; 1.
DR SMART; SM01195; FA; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00661; FERM_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001073}.
FT DOMAIN 3..287
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 318..343
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 410..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 446..465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 624..668
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 624..648
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 818 AA; 91893 MW; E97C481824537FCE CRC64;
KATLYRVFML DGTEVSVDLP KHAKGQDLFD QIVYHLDLVE TDYFGLQFLD SAQVAHWLDH
AKPIKKQMKI GPAYALHFRV KYYSSEPNNL REEFTRYLFV LQLRHDILSG KLKCPYETAV
ELAALCLQAE LGECELPEHT PELVSEFRFI PNQTEAMEFD IFQRWKECRG KSPAQAELSY
LNKAKWLEMY GVDMHVVRGR DGCEYSLGLT PTGILIFEGA NKIGLFFWPK ITKMDFKKSK
LTLVVVEDDD QGREQEHTFV FRLDSARTCK HLWKCAVEHH AFFRLRTPGN SKSNRSDFIR
LGSRFRFSGR TEYQATHGSR LRRTSTFERK PSKRYPSRRH STFKASNPVI AAQLCSKTNP
EVHNYQPQYH PNIHPSQPRW HPHSPNVSYP LPSPVLSSSD RLPFGIEENG GTPFLTAASG
RHHHQHQHQH QHQHHSNYSL SLTLENKEGP LRSPNSSSKS LTKLSPGTPA LFSEAAAHLK
KLELETVKAA GPWPPLHINI NKAEEKKVSE KTLQTPLLPS PVADHVKCNI LKAQLENASR
VNIQGGKEES TFVNINKKSS LQDPSVRSPI PIRVETAQPP VEKPEIKPPR VRKLTRQYSF
DEDDLPPDLA EAVGVTTATT TNTTTAATQV SVPLPSPKVQ NVSSPHKSEG KGPLSPGAKS
PSDRGGAFTL EPGDLLMDFT EATPLAEPAS NPHCAHSRCS PPLSLPMKEE TTGVCMYPPI
KTRLIKTFPV DTMNPFPDAF TTGPQFTADF RDSKLQCCPG PTSPLIPAAT LRPLTETVST
VQTIYTTRKP VSLAASAETL RQELEREKMM KRLLMTEL
//
