ID G1S918_NOMLE Unreviewed; 382 AA.
AC G1S918;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Proline and arginine rich end leucine rich repeat protein {ECO:0000313|Ensembl:ENSNLEP00000022007.1};
GN Name=PRELP {ECO:0000313|Ensembl:ENSNLEP00000022007.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000022007.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000022007.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000022007.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01023462; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003264632.1; XM_003264584.2.
DR RefSeq; XP_012357522.1; XM_012502068.1.
DR AlphaFoldDB; G1S918; -.
DR STRING; 61853.ENSNLEP00000022007; -.
DR Ensembl; ENSNLET00000023121.2; ENSNLEP00000022007.1; ENSNLEG00000018115.2.
DR GeneID; 100602848; -.
DR KEGG; nle:100602848; -.
DR CTD; 5549; -.
DR eggNOG; KOG0619; Eukaryota.
DR GeneTree; ENSGT00940000160163; -.
DR HOGENOM; CLU_000288_186_4_1; -.
DR InParanoid; G1S918; -.
DR OMA; ELRWVNL; -.
DR OrthoDB; 521898at2759; -.
DR TreeFam; TF334562; -.
DR Proteomes; UP000001073; Chromosome 9.
DR GO; GO:0090398; P:cellular senescence; IEA:Ensembl.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR PANTHER; PTHR45712; AGAP008170-PA; 1.
DR PANTHER; PTHR45712:SF8; PROLARGIN; 1.
DR Pfam; PF13855; LRR_8; 3.
DR Pfam; PF01462; LRRNT; 1.
DR SMART; SM00364; LRR_BAC; 4.
DR SMART; SM00369; LRR_TYP; 8.
DR SMART; SM00013; LRRNT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 2.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..382
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003421785"
FT DOMAIN 72..106
FT /note="LRRNT"
FT /evidence="ECO:0000259|SMART:SM00013"
FT REGION 19..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..66
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 382 AA; 43823 MW; 02402EC42DD00958 CRC64;
MRSPLCWLLP LLILASVAQG QPTRRPRPGT GPGRRPRPRP RPTPSFPQPH EPAEPTDLPP
PLPPGPPSVF PDCPRECYCP PDFPSALYCD SRNLRKVPII PPRIHYLYLQ NNFITELPVE
SFQNATGLRW INLDNNRIRK IDQRVLEKLP GLVFLYMEKN QLEEVPSALP RNLEQLRLSQ
NHISRIPPGV FSKLENLLLL DLQHNRLSDG VFKPDTFQGL KNLMQLNLAH NILRKMPPRV
PTAIHQLYLD SNKIETIPNG YFKSFPNLAF IRLNYNKLTD RGLPKNSFNI SNLLVLHLSH
NRISSVPAIN NRLEHLYLNN NSIEKINGTQ ICPNDLVAFH DFSSDLENVP HLRYLRLDGN
YLKPPIPLDL MMCFRLLQSV VI
//
