UniProt: G1S983

Database: UniProt
Entry: G1S983_NOMLE

LinkDB:  G1S983_NOMLE 
Original site:  G1S983_NOMLE

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Ontology (3)   
   GO (3)   
Gene (5)   
   KEGG GENES (1)   
   NCBI-Gene (1)   
   ENSEMBL-UP (3)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   EMBL (1)   
Protein domain (6)   
   InterPro (3)   
   Pfam (1)   
   PROSITE (2)   
All databases (16)   

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ID   G1S983_NOMLE            Unreviewed;       318 AA.
AC   G1S983;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 73.
DE   RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};
GN   Name=OR52D1 {ECO:0000313|Ensembl:ENSNLEP00000022072.1};
OS   Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC   Nomascus.
OX   NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000022072.1, ECO:0000313|Proteomes:UP000001073};
RN   [1] {ECO:0000313|Ensembl:ENSNLEP00000022072.1, ECO:0000313|Proteomes:UP000001073}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Gibbon Genome Sequencing Consortium;
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSNLEP00000022072.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363047};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363047}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000256|RuleBase:RU000688}.
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DR   EMBL; ADFV01111903; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_003254881.1; XM_003254833.2.
DR   AlphaFoldDB; G1S983; -.
DR   STRING; 61853.ENSNLEP00000022072; -.
DR   Ensembl; ENSNLET00000023188.2; ENSNLEP00000022072.1; ENSNLEG00000018163.2.
DR   GeneID; 100585654; -.
DR   KEGG; nle:100585654; -.
DR   eggNOG; ENOG502SHDP; Eukaryota.
DR   GeneTree; ENSGT01090000260043; -.
DR   HOGENOM; CLU_012526_0_0_1; -.
DR   InParanoid; G1S983; -.
DR   OMA; FRSMAIV; -.
DR   OrthoDB; 4578140at2759; -.
DR   TreeFam; TF343679; -.
DR   Proteomes; UP000001073; Chromosome 15.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR   CDD; cd15221; 7tmA_OR52B-like; 1.
DR   Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR000725; Olfact_rcpt.
DR   PANTHER; PTHR26450:SF75; OLFACTORY RECEPTOR 52D1; 1.
DR   PANTHER; PTHR26450; OLFACTORY RECEPTOR 56B1-RELATED; 1.
DR   Pfam; PF13853; 7tm_4; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00245; OLFACTORYR.
DR   SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|RuleBase:RU363047};
KW   G-protein coupled receptor {ECO:0000256|RuleBase:RU000688};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363047};
KW   Olfaction {ECO:0000256|RuleBase:RU363047};
KW   Receptor {ECO:0000256|RuleBase:RU000688};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW   Sensory transduction {ECO:0000256|RuleBase:RU363047};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|RuleBase:RU000688};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000688};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM        28..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363047"
FT   TRANSMEM        60..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363047"
FT   TRANSMEM        143..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363047"
FT   TRANSMEM        187..209
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363047"
FT   TRANSMEM        215..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363047"
FT   TRANSMEM        244..264
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363047"
FT   TRANSMEM        276..298
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363047"
FT   DOMAIN          44..296
FT                   /note="G-protein coupled receptors family 1 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50262"
SQ   SEQUENCE   318 AA;  35191 MW;  72FD94CE8A94AB6C CRC64;
     MSDSNLSDNR LPDTFFLTGI PGLETAHFWI AIPFCAMYLV ALAGNATLIL VIAMDNALHA
     PMYLFLCLLS LTDLALSSTT VPKMLAILWL HAGEISFGGC LAQMFCVHSI YALESSILLA
     MAFDRYVAIC NPLRYTTILN HAVIGRIGFV GLFRSVAIVS PFIFLLRRLP YCGHRVMTHT
     YCEHMGIARL ACANITVNIV YGLTVALLAM GLDSILIAIS YGFILHAVFH LPSRDAQHKA
     LSTCGSHIGI ILVFYIPAFF SFLTHRFGHH QVPKHVHIFL ANLYVLVPPV LNPIIYGART
     KEIRSRLLKL LHLGKTSI
//

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