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Database: UniProt
Entry: G1SAM0_NOMLE
LinkDB: G1SAM0_NOMLE
Original site: G1SAM0_NOMLE 
ID   G1SAM0_NOMLE            Unreviewed;       395 AA.
AC   G1SAM0;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   16-OCT-2019, entry version 46.
DE   RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN   Name=NHLRC1 {ECO:0000313|Ensembl:ENSNLEP00000022564};
OS   Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates
OS   leucogenys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hylobatidae; Nomascus.
OX   NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000022564};
RN   [1] {ECO:0000313|Ensembl:ENSNLEP00000022564}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
RN   [2] {ECO:0000313|Ensembl:ENSNLEP00000022564}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Gibbon Genome Sequencing Consortium;
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; ADFV01015940; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_003263597.1; XM_003263549.3.
DR   STRING; 61853.ENSNLEP00000022564; -.
DR   Ensembl; ENSNLET00000023710; ENSNLEP00000022564; ENSNLEG00000018685.
DR   GeneID; 100591742; -.
DR   KEGG; nle:100591742; -.
DR   CTD; 378884; -.
DR   eggNOG; ENOG410ITF2; Eukaryota.
DR   eggNOG; ENOG410ZMHC; LUCA.
DR   GeneTree; ENSGT00730000111361; -.
DR   InParanoid; G1SAM0; -.
DR   KO; K10602; -.
DR   OMA; WGTLINP; -.
DR   OrthoDB; 711255at2759; -.
DR   TreeFam; TF331018; -.
DR   Proteomes; UP000001073; Chromosome 8.
DR   GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR   GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:Ensembl.
DR   GO; GO:0006914; P:autophagy; IEA:Ensembl.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IEA:Ensembl.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0000209; P:protein polyubiquitination; IEA:Ensembl.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0045859; P:regulation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:1903076; P:regulation of protein localization to plasma membrane; IEA:Ensembl.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IEA:Ensembl.
DR   Gene3D; 2.120.10.30; -; 2.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR013017; NHL_repeat_subgr.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   Pfam; PF14634; zf-RING_5; 1.
DR   SMART; SM00184; RING; 1.
DR   PROSITE; PS51125; NHL; 6.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001073};
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT   DOMAIN       26     72       RING-type. {ECO:0000259|PROSITE:PS50089}.
FT   REPEAT      113    157       NHL. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00504}.
FT   REPEAT      161    204       NHL. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00504}.
FT   REPEAT      212    245       NHL. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00504}.
FT   REPEAT      248    300       NHL. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00504}.
FT   REPEAT      301    349       NHL. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00504}.
FT   REPEAT      350    393       NHL. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00504}.
SQ   SEQUENCE   395 AA;  42259 MW;  06E92017F121C647 CRC64;
     MAAEASESGP GLQELMREAE ISLLECKVCF EKFGHRQQRR PRNLSCGHVV CLACVASLAH
     PRTLALECPF CRRACRGCDT SDCLPVLHLI ELLGSALRQS PAAHRAAPSA PGALTCHHTF
     GGWGTLVNPT GLALCPKTGR VVVVHDGRRR VKIFDSGGGC AHQFGEKGDA AQDIRYPVDV
     TVTNDCHVVV TDAGDRSIKV FDFFGQIKLV IGGQFSLPWG VETTPENGIV VTDADAGSLH
     LLDVDFAEGV LRRTERLQAH LCNPRGVAVS WLTGAIAVLE HPLALGTGVC STRVKVFSSS
     MQLVGQVDTF GLSLYFPSKI TASAVTFDHQ GNVIVADTSG PAILCLGKPE EFPVPKPMVT
     HGLSHPVALT FTKENSLLVL DTASHSIKVY KVDWG
//
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