ID G1SEP7_RABIT Unreviewed; 569 AA.
AC G1SEP7;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=CAP-Gly domain containing linker protein family member 4 {ECO:0000313|Ensembl:ENSOCUP00000000937.4};
GN Name=CLIP4 {ECO:0000313|Ensembl:ENSOCUP00000000937.4};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000000937.4, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000000937.4, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke inbred {ECO:0000313|Ensembl:ENSOCUP00000000937.4,
RC ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000000937.4}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000000937.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAGW02005753; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAGW02005754; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAGW02005755; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1SEP7; -.
DR Ensembl; ENSOCUT00000001082.4; ENSOCUP00000000937.4; ENSOCUG00000001082.4.
DR eggNOG; KOG4568; Eukaryota.
DR GeneTree; ENSGT00940000157706; -.
DR HOGENOM; CLU_023687_1_0_1; -.
DR TreeFam; TF326096; -.
DR Proteomes; UP000001811; Chromosome 2.
DR Bgee; ENSOCUG00000001082; Expressed in testis and 15 other cell types or tissues.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 3.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR PANTHER; PTHR18916:SF32; CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 4; 1.
DR PANTHER; PTHR18916; DYNACTIN 1-RELATED MICROTUBULE-BINDING; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF01302; CAP_GLY; 3.
DR SMART; SM01052; CAP_GLY; 3.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF74924; Cap-Gly domain; 3.
DR PROSITE; PS50088; ANK_REPEAT; 1.
DR PROSITE; PS00845; CAP_GLY_1; 2.
DR PROSITE; PS50245; CAP_GLY_2; 3.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000001811}.
FT REPEAT 51..83
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 168..210
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT DOMAIN 369..411
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT DOMAIN 508..550
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT REGION 282..332
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..332
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 569 AA; 60181 MW; 7E947B343CC56DAB CRC64;
GTSAGSCIRS GAGDVETAVK FAGRLLELGA DVIDILVMFI ADVDATCSDF DFGTALHIAA
YNLCAGAVRC LLEHGANPAF RNDKGQMAAD VVPDPVDMPL EMADAAATAK EIRQMLLAAA
PLSCSVPKAL LPNGAAAPGK AMLTSLGLKL GDRVVIAGQK VGTLRFCGKT EFASGQWAGI
ELDEPEGKNN GSVGKVQYFK CAPKYGIFAP LSKISKAKDR RKNVVHGPST KAIPLIRSQK
IEVAHITSKV NTGLMTSKKD ITSESTLSLP PGEELKTVIE KDGPTLGSAS SSSSTSSLEH
KQSNAKKLSA SGSTKKTMSK SPSLSSRASA GLNSSATSVA NSSCREGELQ LGDRVLVVGQ
RVGTVRFFGT TNFAPGYWYG IELEKPHGKN DGSVGGVQYF SCSPRYGIFA PPSRVQRITD
SLDTLSEISS NKQNHSYPGF RRSFSTTSAS SQKEVSRRNA FAKSKTALRR SWSTSTSGGG
LEGSVRLHEG SQVLLTSSNE MCTVRYVGPT DFASGMWLGL ELRSARGKND GAVGDRRYFT
CKPNHGVLVR PSRVTYRGIN GSKLVGENC
//
