ID G1SET9_RABIT Unreviewed; 200 AA.
AC G1SET9;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=LHFPL tetraspan subfamily member 6 {ECO:0000313|Ensembl:ENSOCUP00000000987.3};
GN Name=LHFPL6 {ECO:0000313|Ensembl:ENSOCUP00000000987.3};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000000987.3, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000000987.3, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke {ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000000987.3}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000000987.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_008272723.1; XM_008274501.2.
DR RefSeq; XP_017206096.1; XM_017350607.1.
DR RefSeq; XP_017206097.1; XM_017350608.1.
DR RefSeq; XP_017206098.1; XM_017350609.1.
DR RefSeq; XP_017206099.1; XM_017350610.1.
DR AlphaFoldDB; G1SET9; -.
DR SMR; G1SET9; -.
DR STRING; 9986.ENSOCUP00000000987; -.
DR Ensembl; ENSOCUT00000001137.4; ENSOCUP00000000987.3; ENSOCUG00000001137.4.
DR GeneID; 100355488; -.
DR KEGG; ocu:100355488; -.
DR CTD; 10186; -.
DR eggNOG; KOG4026; Eukaryota.
DR GeneTree; ENSGT00990000203589; -.
DR HOGENOM; CLU_084868_2_0_1; -.
DR InParanoid; G1SET9; -.
DR OrthoDB; 2917854at2759; -.
DR TreeFam; TF321143; -.
DR Proteomes; UP000001811; Unplaced.
DR Bgee; ENSOCUG00000001137; Expressed in aorta and 18 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.140.150; -; 1.
DR InterPro; IPR019372; LHFPL.
DR PANTHER; PTHR12489:SF12; LHFPL TETRASPAN SUBFAMILY MEMBER 6 PROTEIN; 1.
DR PANTHER; PTHR12489; LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN; 1.
DR Pfam; PF10242; L_HMGIC_fpl; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001811};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..200
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5023898096"
FT TRANSMEM 87..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 120..141
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 200 AA; 21586 MW; 140A095E07F25FF9 CRC64;
MASSLTCTGV IWALLSFLCA ATSCVGFFMP YWLWGSQLGK SVSFGTFRRC SYPVHDESRQ
MMVMVEECGR YASFQGIPSA EWRICTVVTG LGCGLLLLVA LTALMGCCVS ELISRTVGRV
AGGIQFLGGL LIGAGCALYP LGWDSEEVRQ TCGYISGQFD LGKCEIGWAY YCTGAGAAAS
MLLCTWLACF SGKKQKHYPY
//
