ID   G1SG30_RABIT            Unreviewed;       257 AA.
AC   G1SG30;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   11-DEC-2019, sequence version 2.
DT   27-MAR-2024, entry version 54.
DE   SubName: Full=Nipsnap homolog 2 {ECO:0000313|Ensembl:ENSOCUP00000001517.3};
GN   Name=NIPSNAP2 {ECO:0000313|Ensembl:ENSOCUP00000001517.3};
OS   Oryctolagus cuniculus (Rabbit).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX   NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000001517.3, ECO:0000313|Proteomes:UP000001811};
RN   [1] {ECO:0000313|Ensembl:ENSOCUP00000001517.3, ECO:0000313|Proteomes:UP000001811}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Thorbecke {ECO:0000313|Proteomes:UP000001811};
RX   PubMed=21993624; DOI=10.1038/nature10530;
RA   Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA   Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA   Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA   Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA   Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA   Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA   Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA   Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA   Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA   Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA   Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA   Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA   Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA   Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA   Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT   "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL   Nature 478:476-482(2011).
RN   [2] {ECO:0000313|Ensembl:ENSOCUP00000001517.3}
RP   IDENTIFICATION.
RC   STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000001517.3};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the NipSnap family.
CC       {ECO:0000256|ARBA:ARBA00005291}.
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DR   AlphaFoldDB; G1SG30; -.
DR   Ensembl; ENSOCUT00000001766.3; ENSOCUP00000001517.3; ENSOCUG00000001768.4.
DR   eggNOG; KOG3447; Eukaryota.
DR   GeneTree; ENSGT00950000183018; -.
DR   HOGENOM; CLU_073626_5_0_1; -.
DR   TreeFam; TF326484; -.
DR   Proteomes; UP000001811; Unplaced.
DR   Bgee; ENSOCUG00000001768; Expressed in heart and 15 other cell types or tissues.
DR   Gene3D; 3.30.70.100; -; 2.
DR   InterPro; IPR011008; Dimeric_a/b-barrel.
DR   InterPro; IPR012577; NIPSNAP.
DR   PANTHER; PTHR21017; NIPSNAP-RELATED; 1.
DR   PANTHER; PTHR21017:SF14; PROTEIN NIPSNAP HOMOLOG 2; 1.
DR   Pfam; PF07978; NIPSNAP; 1.
DR   SUPFAM; SSF54909; Dimeric alpha+beta barrel; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001811}.
FT   DOMAIN          158..255
FT                   /note="NIPSNAP"
FT                   /evidence="ECO:0000259|Pfam:PF07978"
SQ   SEQUENCE   257 AA;  30639 MW;  A297F94575BA128E CRC64;
     MRRLTSSNNR PREDSWLKSL FVRKVDPRKD AHSNLLAKKE TSSLYKLQFH NVKPECLDAY
     NKICQEVLPK IHEDKHYPCT LVGTWNTWYG EQDQAVHLWR YEGGYPALTE VMNKLRENQE
     FVSFRKARSD MLLSRKNQLL LEFSFWNEPV PRSGPNIYEL RSYQLRPGTM IEWGNYWARA
     IRFRQDGNEA VGGFFSQIGQ LYMVHHLWAY KDLQTREDIR NAAWHKHGWE ELVYYTVPLI
     QEMESRIMIP LKTSPLQ
//