ID G1SJP0_RABIT Unreviewed; 406 AA.
AC G1SJP0;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 2.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=Alpha/beta hydrolase fold-3 domain-containing protein {ECO:0000259|Pfam:PF07859};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000002964.3, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000002964.3, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke {ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000002964.3}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000002964.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_002721559.1; XM_002721513.3.
DR AlphaFoldDB; G1SJP0; -.
DR SMR; G1SJP0; -.
DR STRING; 9986.ENSOCUP00000002964; -.
DR MEROPS; S09.A48; -.
DR PaxDb; 9986-ENSOCUP00000002964; -.
DR Ensembl; ENSOCUT00000003419.4; ENSOCUP00000002964.3; ENSOCUG00000003422.4.
DR GeneID; 100349449; -.
DR KEGG; ocu:100349449; -.
DR CTD; 343066; -.
DR eggNOG; KOG1515; Eukaryota.
DR GeneTree; ENSGT00940000157630; -.
DR HOGENOM; CLU_012494_12_2_1; -.
DR InParanoid; G1SJP0; -.
DR OMA; CHLQEGF; -.
DR OrthoDB; 1144477at2759; -.
DR TreeFam; TF314978; -.
DR Proteomes; UP000001811; Unplaced.
DR Bgee; ENSOCUG00000003422; Expressed in zone of skin and 3 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR013094; AB_hydrolase_3.
DR PANTHER; PTHR48081; AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C; 1.
DR PANTHER; PTHR48081:SF32; ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF07859; Abhydrolase_3; 2.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001811};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 40..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 114..260
FT /note="Alpha/beta hydrolase fold-3"
FT /evidence="ECO:0000259|Pfam:PF07859"
FT DOMAIN 309..378
FT /note="Alpha/beta hydrolase fold-3"
FT /evidence="ECO:0000259|Pfam:PF07859"
SQ SEQUENCE 406 AA; 45660 MW; DD217EAC73C37BC3 CRC64;
MVLLWLLLWG LPTFLLGVFL WVVLVHFFTT HIPASMQHPA KVRFLHCLFL YVITLGNILE
KLGICPMPKF ARFVHDLVII KKDPKVAVTN LRFGSVPVRL FQPTAPSSGP RRGIIFYHGG
GAVFGSLDCY HSLCSFLARE TDSVVLSVGY RKLPDYHSPI ITKDCLNASI HFLKALDTYG
VDPARVVLCG ESIGGGAVAV TTQSLVGRPD LPRIRAQVLI NPIVQAVNLQ LPSFRQNQRV
PFLTRKFVVT VVCQYMNIHR SWHRALLTGA FIPPEAWSKY KKWLSSDNIP KRFKTKSHQP
SFPAPFNEAA YLEMKHLLDV ENSPILAEDE VIAQLPEAFV VSCGNDILRD DALLYRKRLE
DQGVPVTWHH AEDGFHGSVI LFDKKHLSFP CSQEIMNAVV CYIKGI
//
