ID G1SJY0_RABIT Unreviewed; 430 AA.
AC G1SJY0;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE RecName: Full=Small ribosomal subunit protein uS5m {ECO:0000256|ARBA:ARBA00039335};
DE AltName: Full=28S ribosomal protein S5, mitochondrial {ECO:0000256|ARBA:ARBA00041606};
GN Name=MRPS5 {ECO:0000313|Ensembl:ENSOCUP00000003074.2};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000003074.2, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000003074.2, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke inbred {ECO:0000313|Ensembl:ENSOCUP00000003074.2,
RC ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000003074.2}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000003074.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS5 family.
CC {ECO:0000256|ARBA:ARBA00008945, ECO:0000256|RuleBase:RU003823}.
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DR EMBL; AAGW02007403; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_002709627.1; XM_002709581.3.
DR AlphaFoldDB; G1SJY0; -.
DR SMR; G1SJY0; -.
DR STRING; 9986.ENSOCUP00000003074; -.
DR PaxDb; 9986-ENSOCUP00000003074; -.
DR Ensembl; ENSOCUT00000003548.4; ENSOCUP00000003074.2; ENSOCUG00000003547.4.
DR GeneID; 100337880; -.
DR KEGG; ocu:100337880; -.
DR CTD; 64969; -.
DR eggNOG; KOG2646; Eukaryota.
DR GeneTree; ENSGT00390000001878; -.
DR HOGENOM; CLU_050434_0_0_1; -.
DR InParanoid; G1SJY0; -.
DR OMA; LICHRAI; -.
DR OrthoDB; 5479674at2759; -.
DR TreeFam; TF313823; -.
DR Proteomes; UP000001811; Chromosome 2.
DR Bgee; ENSOCUG00000003547; Expressed in heart and 16 other cell types or tissues.
DR GO; GO:0005763; C:mitochondrial small ribosomal subunit; IEA:Ensembl.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:UniProtKB-UniRule.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR Gene3D; 3.30.160.20; -; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR000851; Ribosomal_uS5.
DR InterPro; IPR005324; Ribosomal_uS5_C.
DR InterPro; IPR013810; Ribosomal_uS5_N.
DR InterPro; IPR018192; Ribosomal_uS5_N_CS.
DR InterPro; IPR048584; Ribosomal_uS5m_N.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR PANTHER; PTHR48277; MITOCHONDRIAL RIBOSOMAL PROTEIN S5; 1.
DR PANTHER; PTHR48277:SF1; MITOCHONDRIAL RIBOSOMAL PROTEIN S5; 1.
DR Pfam; PF00333; Ribosomal_S5; 1.
DR Pfam; PF03719; Ribosomal_S5_C; 1.
DR Pfam; PF21251; S5p_N; 1.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS00585; RIBOSOMAL_S5; 1.
DR PROSITE; PS50881; S5_DSRBD; 1.
PE 3: Inferred from homology;
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000001811};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274, ECO:0000256|PROSITE-
KW ProRule:PRU00268};
KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980, ECO:0000256|PROSITE-
KW ProRule:PRU00268}.
FT DOMAIN 218..282
FT /note="S5 DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50881"
FT REGION 108..128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 180..211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 430 AA; 47955 MW; 944BA82940D4CA6C CRC64;
MAAAVLAARC VPGLCGVQAG LLWSRQLSLN TFPAASVLAW KTALSNGPVS SRGSRDSRGD
ASLSHALQTQ CWISSPSAWT GQQHRAYSFF TKLTADELWK GALAETGAGA RKGRGKRTKR
KRRKDLNRGQ IIGEGRSGFL WPGLNVPLMK NGAVQTITQR SKEEQAKVEA DMIQQREEWD
RKRKTKVKRE RGWSGNTWGG VSLGPPDPGP NGETYEDFDT RVLEVRNVFN MTAKEGRRKS
VRVLVAVGNG KGAAGFAVGK ATERIDAFRK AKNKAIHYLH YIERYEDHTI FHDISLRFKR
THIRMKKQPR GYGLRCHRAI ITICRLIGIK DMYAKVSGSV NMLNLTRGLF QGLSRQETHQ
QLADKKGLHV VEFREECGPL PIVVASPQGA LRKDPEPEDE VPDIKLDWQE VKAAQGLKRS
VWANLKRAAT
//
