ID G1SMA7_RABIT Unreviewed; 583 AA.
AC G1SMA7;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=NudC domain-containing protein 1 {ECO:0000256|ARBA:ARBA00018915};
GN Name=NUDCD1 {ECO:0000313|Ensembl:ENSOCUP00000004041.3};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000004041.3, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000004041.3, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke inbred {ECO:0000313|Ensembl:ENSOCUP00000004041.3,
RC ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000004041.3}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000004041.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AAGW02012833; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAGW02012834; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_002710782.1; XM_002710736.3.
DR AlphaFoldDB; G1SMA7; -.
DR SMR; G1SMA7; -.
DR STRING; 9986.ENSOCUP00000004041; -.
DR PaxDb; 9986-ENSOCUP00000004041; -.
DR Ensembl; ENSOCUT00000004677.3; ENSOCUP00000004041.3; ENSOCUG00000004673.4.
DR GeneID; 100347475; -.
DR KEGG; ocu:100347475; -.
DR CTD; 84955; -.
DR eggNOG; KOG4379; Eukaryota.
DR GeneTree; ENSGT00390000007776; -.
DR HOGENOM; CLU_021010_1_0_1; -.
DR InParanoid; G1SMA7; -.
DR OrthoDB; 3664873at2759; -.
DR TreeFam; TF323350; -.
DR Proteomes; UP000001811; Chromosome 3.
DR Bgee; ENSOCUG00000004673; Expressed in liver and 15 other cell types or tissues.
DR ExpressionAtlas; G1SMA7; baseline.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR Gene3D; 2.60.40.790; -; 1.
DR InterPro; IPR007052; CS_dom.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR InterPro; IPR037895; NUDCD1.
DR PANTHER; PTHR21664; CHRONIC MYELOGENOUS LEUKEMIA TUMOR ANTIGEN 66; 1.
DR PANTHER; PTHR21664:SF1; NUDC DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF04969; CS; 1.
DR SUPFAM; SSF49764; HSP20-like chaperones; 1.
DR PROSITE; PS51203; CS; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001811}.
FT DOMAIN 273..361
FT /note="CS"
FT /evidence="ECO:0000259|PROSITE:PS51203"
SQ SEQUENCE 583 AA; 67024 MW; 94F78024D854BC95 CRC64;
MEVAANCSLR VKRPLLDPRF EGYKLSLEPL PCYQLELDAA VAEVKLRDDQ YTLEHMHAFG
MYNYLHCDSW NQDSVYYIDN LGRIMNLTVM LDTALGKPRE VFRLPTDLTA YDNRLCASLY
FTSSTWVTLS DGTGRLYVIA TGERGNSASE KWEIMFNEEL GNPFIIIHSI SLQKMEEHSI
AILLLRIEKE DLDMKGSGFY VSLEWVTISN KNKDTKKYEI IKRDTLSGKS VPHYAAIEPD
GNGLMIASYK SFQFVQTGQN FEENMDEDTS EKIKEPLYYW QQTEDDLTVT IRLPEDSRKE
DIQVQFLPEH INIVLRDQQI LEGKLYSLID HESSTWIIKE NNSLEISLIK KNEGMTWPEL
VIGDKQGELI RDSAQCAAIA ERLMHLTSEE LNPNPDKEKP PCNAQELEEC DIFFEESSSL
CRFDGNTLKT THVVSLGSNQ YLFSVVVDPK EMPCFCLRHD VDALLWQPHS SRQDDMWEHI
ATFNALGYVQ ASKRDKKFFA CAPNYSYAAL CECLRRVFIY RQPTPMSTVL YNRKEGRKVG
QVAKQQVASL ETNDPILGFQ ATNERLFVLT TKNLFLIKVN TEN
//
