ID G1SP55_RABIT Unreviewed; 722 AA.
AC G1SP55;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Ataxin 7 like 2 {ECO:0000313|Ensembl:ENSOCUP00000004807.4};
GN Name=ATXN7L2 {ECO:0000313|Ensembl:ENSOCUP00000004807.4};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000004807.4, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000004807.4, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke inbred {ECO:0000313|Ensembl:ENSOCUP00000004807.4,
RC ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000004807.4}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000004807.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAGW02000967; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_008262966.1; XM_008264744.2.
DR AlphaFoldDB; G1SP55; -.
DR SMR; G1SP55; -.
DR STRING; 9986.ENSOCUP00000004807; -.
DR PaxDb; 9986-ENSOCUP00000004807; -.
DR Ensembl; ENSOCUT00000005538.4; ENSOCUP00000004807.4; ENSOCUG00000005546.3.
DR GeneID; 100340504; -.
DR CTD; 127002; -.
DR eggNOG; ENOG502QVN4; Eukaryota.
DR GeneTree; ENSGT00940000159736; -.
DR HOGENOM; CLU_019888_1_0_1; -.
DR InParanoid; G1SP55; -.
DR OrthoDB; 1385477at2759; -.
DR TreeFam; TF331337; -.
DR Proteomes; UP000001811; Chromosome 13.
DR Bgee; ENSOCUG00000005546; Expressed in blood and 17 other cell types or tissues.
DR Gene3D; 6.10.140.1270; -; 1.
DR InterPro; IPR013243; SCA7_dom.
DR PANTHER; PTHR15117; ATAXIN 7 RELATED; 1.
DR PANTHER; PTHR15117:SF5; ATAXIN-7-LIKE PROTEIN 2; 1.
DR Pfam; PF08313; SCA7; 1.
DR PROSITE; PS51505; SCA7; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001811}.
FT DOMAIN 230..297
FT /note="SCA7"
FT /evidence="ECO:0000259|PROSITE:PS51505"
FT REGION 107..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 288..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 350..397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 461..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 531..657
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..163
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..304
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 464..478
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 479..497
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 531..553
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 557..571
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 722 AA; 76509 MW; 5F5E48636160BDDD CRC64;
MAVRERAAAA MAALERRVPS LDDFAGQSWS SWVERADLPA ADGAELEESS KNTKKLDAMT
LIKEDMSIFG HCPAHDDFYL VVCNHCSQVV KPQAFQKHCE RRHGPLSKLY ARAPPPPPAP
ASSQKCHVVN GQGPACRAPG STKTSSREKG QGSRSRGHQP PEKTQKDNLC QAGGLTKDSP
GKPPTAPPSK EPPGRENIEI IPSEGSSHRA EGSPPEKEPG GARLPPKSHR KMARKECDLN
RQCGVINPET KKICTRLLTC KIHSVHQRRE VQGRAKDFDV LVAELKANSR KGESPKEKSP
GCKEPALERP SQEPPCSVPV VAAAAAPSST FSARSKQTYP YCALPRSRAS SESEVDDEGP
CGGDGDPGLF PFPLPRGGAQ ASSEESEEEG TSDDLHLPPD CHYATRPPRP QAFCTFGSRL
VSPGCYVFSR RLDRFCSALS SMLERHLSSH MWKKIPPAAE PASHLVSSPS SAPLSPPSTG
SCPRLPGPPP RPACPASTPP TKDSLVPSYP AGSPSVAAAC SQAECTGGSQ AITSPLPANT
PSPSFSKLPP SKASKSSKGK DGAEAEAPSR KRKLSPGPTT FRRTCVLEPA GKGKPSGCRG
LSAKTKTALG VGLNGTVGPR MKRAGPLDCR GPPHQPPTPV KASQLENRGA AGHPAKALPT
NCLSEEEVAK KRKNLATYCR PVKAKHCQPG APADAACSVR RKKPGPALAF EEKCSTLKSK
AH
//
