ID G1SU22_RABIT Unreviewed; 368 AA.
AC G1SU22;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Fc receptor like A {ECO:0000313|Ensembl:ENSOCUP00000006831.3};
GN Name=FCRLA {ECO:0000313|Ensembl:ENSOCUP00000006831.3};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000006831.3, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000006831.3, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke inbred {ECO:0000313|Ensembl:ENSOCUP00000006831.3,
RC ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000006831.3}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000006831.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAGW02000248; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1SU22; -.
DR PaxDb; 9986-ENSOCUP00000006831; -.
DR Ensembl; ENSOCUT00000007905.4; ENSOCUP00000006831.3; ENSOCUG00000007906.4.
DR eggNOG; ENOG502T149; Eukaryota.
DR GeneTree; ENSGT01050000244808; -.
DR HOGENOM; CLU_063170_0_0_1; -.
DR TreeFam; TF335097; -.
DR Proteomes; UP000001811; Chromosome 13.
DR Bgee; ENSOCUG00000007906; Expressed in blood and 6 other cell types or tissues.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR11481:SF71; FC RECEPTOR-LIKE A; 1.
DR PANTHER; PTHR11481; IMMUNOGLOBULIN FC RECEPTOR; 1.
DR Pfam; PF13895; Ig_2; 2.
DR SMART; SM00409; IG; 2.
DR SMART; SM00408; IGc2; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001811};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..31
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 32..368
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5023845207"
FT DOMAIN 80..174
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 180..266
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 255..322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 255..291
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 292..309
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 368 AA; 39840 MW; 670D31373D25B9DB CRC64;
MKLGSVFTSW TLHLSPGMLW AALMFLASLS GSPWTVPSSA ANLETLQCDG PISTRKSSCH
TDADPRDDDY EIKAYTFSEP FHLIVSYDWL ILQSPSNHLF EGDPLILRCR AWQDWPLTQV
TFYRDGSALG PPGPNKDFSI AAVQKADSGR YHCSGVFRSP GPGSPETAAA VAITVQELFP
APVLQAAPSG SQDGSLMTLS CQTKLPPQKS ATRLLFSFYK DGKPMRSRGR SSEFQIPIAA
EEHSGTYWCE AATEDNQVQK QSPQLEMRVH ASSGTAAPPT LNPAPQKSAA PETTPTEPPG
PPPPQPTPAS EDSGFSSPLR APDPHLYHRM GLLLQHIQDV RALLGHLVIE LRNLSGHLKP
GTTEAPAK
//
