ID G1T527_RABIT Unreviewed; 530 AA.
AC G1T527;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Zinc finger protein 385C {ECO:0000313|Ensembl:ENSOCUP00000011419.3};
GN Name=ZNF385C {ECO:0000313|Ensembl:ENSOCUP00000011419.3};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000011419.3, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000011419.3, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke inbred {ECO:0000313|Ensembl:ENSOCUP00000011419.3,
RC ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000011419.3}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000011419.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAGW02039745; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAGW02039746; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAGW02039747; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1T527; -.
DR STRING; 9986.ENSOCUP00000011419; -.
DR PaxDb; 9986-ENSOCUP00000011419; -.
DR Ensembl; ENSOCUT00000013269.3; ENSOCUP00000011419.3; ENSOCUG00000013271.4.
DR eggNOG; ENOG502QTBM; Eukaryota.
DR GeneTree; ENSGT00940000157202; -.
DR HOGENOM; CLU_027876_0_0_1; -.
DR InParanoid; G1T527; -.
DR TreeFam; TF326622; -.
DR Proteomes; UP000001811; Chromosome 19.
DR Bgee; ENSOCUG00000013271; Expressed in prefrontal cortex and 12 other cell types or tissues.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 4.
DR InterPro; IPR003604; Matrin/U1-like-C_Znf_C2H2.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR23067; DOUBLE-STRANDED RNA-BINDING ZINC FINGER PROTEIN; 1.
DR PANTHER; PTHR23067:SF6; ZINC FINGER PROTEIN 385C; 1.
DR Pfam; PF12874; zf-met; 4.
DR SMART; SM00355; ZnF_C2H2; 4.
DR SMART; SM00451; ZnF_U1; 4.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 4.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001811}.
FT DOMAIN 182..204
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS00028"
FT DOMAIN 397..419
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS00028"
FT REGION 1..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 97..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 212..322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 356..394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 408..438
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..49
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 248..266
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 279..293
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 530 AA; 55238 MW; 7939579C91ED116C CRC64;
MLYPSLSLGA PCGPGCLTRS PGMKRPLSPS PPGEKEPPTA GPAECPPRPP EAPKPKRERK
RPSYTLCDVC NIQLNSAAQA QVHCGGRAHQ RRLRQLSLGK SPSGPAGPAS SAPSPLLGSL
PLPTRPLQPP LDLKHLLAFH FNGAAPLSLF PNFSTMDPVQ KAVISHTFGV PSPLKKKLFI
SCNICHLRFN SANQAEAHYK GHKHARKLKA VEAAKNKQRP PTPAQDGAAA ASPTPTPASG
APREPQSKAA PATPPLGPPL QLPSTPDPTS GEPAHSDLLD AASSSSSSSC PPCSPEPGRE
ALGPEPTAAA VGSGVSGDGR GEKGRLYCPT CKVTVNSASQ LQAHNTGAKH RWMVEGQRGA
PRRGRGRPVP RGGPGHKAKK VTGGRNGRQG PTPPFHCALC QLQVNSETQL KQHMSSRRHK
DRLAGKPPKP SPQPSKLQKH AALAMSILKS KLALQKQLTK TLAARFLPSP LPATAICALP
GPLALRPAPN AATAAAAATL FPAPILGPAL FRTPAGTVRP ATGPIVFAPY
//
