ID G1T686_RABIT Unreviewed; 261 AA.
AC G1T686;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOCUP00000011911.3};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000011911.3, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000011911.3, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke inbred {ECO:0000313|Ensembl:ENSOCUP00000011911.3,
RC ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000011911.3}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000011911.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the fibroblast growth factor-binding protein
CC family. {ECO:0000256|ARBA:ARBA00008326}.
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DR EMBL; AAGW02010043; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1T686; -.
DR PaxDb; 9986-ENSOCUP00000011911; -.
DR Ensembl; ENSOCUT00000013846.3; ENSOCUP00000011911.3; ENSOCUG00000016623.3.
DR eggNOG; ENOG502RZQ6; Eukaryota.
DR GeneTree; ENSGT00940000154372; -.
DR HOGENOM; CLU_102227_0_0_1; -.
DR InParanoid; G1T686; -.
DR TreeFam; TF335877; -.
DR Proteomes; UP000001811; Chromosome 2.
DR Bgee; ENSOCUG00000016623; Expressed in heart and 12 other cell types or tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0019838; F:growth factor binding; IEA:UniProtKB-KW.
DR InterPro; IPR010510; FGF1-bd.
DR PANTHER; PTHR15258:SF4; -; 1.
DR PANTHER; PTHR15258; FGF BINDING PROTEIN-RELATED; 1.
DR Pfam; PF06473; FGF-BP1; 1.
PE 3: Inferred from homology;
KW Growth factor binding {ECO:0000256|ARBA:ARBA00023183};
KW Reference proteome {ECO:0000313|Proteomes:UP000001811};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..261
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5023809828"
FT REGION 166..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 261 AA; 28569 MW; 823120B6FDA6A670 CRC64;
MWTRTLTLLS ILLLAAQGLL TEAQSGEQDE GNLEAEQDGW VPLEKPVIVS TSPPTQVIVT
GSFVSRDQAK CNVTVTRREE GVHLQVHCVR LHHEFSCVFA GNPTACLHCL DNDKVYWRQI
GWRLRRLNHI CEDSKAILNT RVCGTKYPES SLTLLSSTLA SKTSVQGLKP TPTVSVKGKQ
PSQTEPSKGK QHAPLCVCSS QESAGWCWDR VCVLPFAAHF LRCVAGSVDF GADSRAHSTV
RVRAGKSCLS GDFSGVHFLL N
//
