ID G1TK45_RABIT Unreviewed; 334 AA.
AC G1TK45;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 2.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Neurotrimin {ECO:0000313|Ensembl:ENSOCUP00000017327.2};
GN Name=NTM {ECO:0000313|Ensembl:ENSOCUP00000017327.2};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000017327.2, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000017327.2, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke inbred {ECO:0000313|Ensembl:ENSOCUP00000017327.2,
RC ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000017327.2}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000017327.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. IgLON family.
CC {ECO:0000256|ARBA:ARBA00037995}.
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DR EMBL; AAGW02009833; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1TK45; -.
DR SMR; G1TK45; -.
DR STRING; 9986.ENSOCUP00000017327; -.
DR PaxDb; 9986-ENSOCUP00000017327; -.
DR Ensembl; ENSOCUT00000032177.3; ENSOCUP00000017327.2; ENSOCUG00000000213.4.
DR eggNOG; KOG3510; Eukaryota.
DR GeneTree; ENSGT00940000158679; -.
DR HOGENOM; CLU_027228_2_2_1; -.
DR InParanoid; G1TK45; -.
DR OMA; EYKCRAK; -.
DR TreeFam; TF325565; -.
DR Proteomes; UP000001811; Chromosome 1.
DR Bgee; ENSOCUG00000000213; Expressed in frontal cortex and 14 other cell types or tissues.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013151; Immunoglobulin.
DR PANTHER; PTHR42757; IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED; 1.
DR PANTHER; PTHR42757:SF9; NEUROTRIMIN; 1.
DR Pfam; PF00047; ig; 1.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 3.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000001811};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 22..93
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 103..185
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 189..276
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 334 AA; 36858 MW; A55C5F0013C74AA7 CRC64;
RLRSDACCFL SPPLTSLSGL LLRCTIDNRV TRVAWLNRST ILYAGNDKWC LDPRVVLLSN
TQTQYSIEIQ NVDVYDEGPY TCSVQTDNHP KTSRVHLIVQ VSPKIVEISS DISINEGNNI
SLTCIATGRP EPTVTWRHIS PKAVGFVSED EYLEIQGITR EQSGDYECSA SNDVAAPVVR
RVKVTVNYPP YISEAKGTGV PVGQKGTLQC EASAVPSAEF QWYKDDKRLM EGKKGVKVEN
RPFLSKLIFF NVSEHDYGNY TCVASNKLGH TNASITLFEL NEPTSSTLLQ EVTTTALTPW
KGPGAVSEVS NGTSRRAGCA WLLSVLVLHL LLKF
//
