ID G1TPZ5_RABIT Unreviewed; 551 AA.
AC G1TPZ5;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=Sushi domain-containing protein {ECO:0000259|PROSITE:PS50923};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000019085.2, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000019085.2, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke inbred {ECO:0000313|Ensembl:ENSOCUP00000019085.2,
RC ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000019085.2}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000019085.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR EMBL; AAGW02025419; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1TPZ5; -.
DR SMR; G1TPZ5; -.
DR STRING; 9986.ENSOCUP00000019085; -.
DR Ensembl; ENSOCUT00000026782.2; ENSOCUP00000019085.2; ENSOCUG00000023993.2.
DR eggNOG; ENOG502SHRK; Eukaryota.
DR GeneTree; ENSGT00940000154640; -.
DR HOGENOM; CLU_020107_5_2_1; -.
DR InParanoid; G1TPZ5; -.
DR TreeFam; TF334137; -.
DR Proteomes; UP000001811; Chromosome 16.
DR Bgee; ENSOCUG00000023993; Expressed in testis and 1 other cell type or tissue.
DR CDD; cd00033; CCP; 7.
DR Gene3D; 1.20.5.3730; -; 1.
DR Gene3D; 2.20.28.230; -; 1.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 6.
DR InterPro; IPR040514; C4bp_oligo.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR19325; COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR19325:SF565; ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 RECEPTOR; 1.
DR Pfam; PF18453; C4bp_oligo; 1.
DR Pfam; PF00084; Sushi; 7.
DR SMART; SM00032; CCP; 7.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 7.
DR PROSITE; PS50923; SUSHI; 7.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Reference proteome {ECO:0000313|Proteomes:UP000001811};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302}.
FT DOMAIN 53..113
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 114..175
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 176..239
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 240..299
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 300..366
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 367..432
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 433..491
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DISULFID 270..297
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 462..489
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 551 AA; 61673 MW; 215F6C0C49BB92B6 CRC64;
MHSPRAPRVF LGKSALHREG GKAAWPLSRL CKVLDPTLFR MTLVAVLLAP VRGDCDPPPI
IPFASPINPL YDLSFKPGTT LKYNCHAGYK KINSTWIICN ANGEWNYNVF CAKKQCKNPG
ELINGKVEVK TDFHLGSIIE FRCLRGYILV GSATSRCEVH GKGVSWSDHI PECVIVKCEA
PPTISNGKHN GMEAVYTYGS VVTYSCDLHY SLLGQASISC VMENTTTGVW SPNPPTCKKI
LCYQPQIPNG IFVSGFGSLH TYKDVIVIKC KKGYALRGSS RIHCEANNEW HPSVPTCELN
SCIDLPELPF ASWEKTAYTS RSPEIFEVGT ELKFKCDPGY RAIPAESLTV KCQENLTWSP
SKGCERVCCP TPDMEKIIII SDRRDFTGIC VYAYGDYVSF MCDKGYYPIS PDGRSSCQVD
GTWNPKMPKC EPARCLKPYI KNAKLSVDKD EYTEFENITI QCDFGYAVVG PPNIICLENR
TWYPEVPKCE WEMAEECEQV MVGRKLLQCL PTPEDVKMAL SVYKLSLEIE RLEQENTQNM
VESSHTSILK A
//
