ID G1TU74_RABIT Unreviewed; 316 AA.
AC G1TU74;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 2.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=Thioredoxin-like fold domain-containing protein {ECO:0000259|Pfam:PF13905};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000020598.2, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000020598.2, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke inbred {ECO:0000313|Ensembl:ENSOCUP00000020598.2,
RC ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000020598.2}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000020598.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAGW02058310; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAGW02058311; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 9986.ENSOCUP00000020598; -.
DR PaxDb; 9986-ENSOCUP00000020598; -.
DR Ensembl; ENSOCUT00000025832.3; ENSOCUP00000020598.2; ENSOCUG00000022990.3.
DR eggNOG; KOG2501; Eukaryota.
DR GeneTree; ENSGT00940000161260; -.
DR HOGENOM; CLU_879870_0_0_1; -.
DR InParanoid; G1TU74; -.
DR TreeFam; TF331873; -.
DR Proteomes; UP000001811; Chromosome 1.
DR Bgee; ENSOCUG00000022990; Expressed in testis and 15 other cell types or tissues.
DR GO; GO:0045494; P:photoreceptor cell maintenance; IEA:InterPro.
DR GO; GO:0007600; P:sensory perception; IEA:InterPro.
DR CDD; cd02964; TryX_like_family; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR029519; RdCVF2.
DR InterPro; IPR012336; Thioredoxin-like_fold.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR46762; NUCLEOREDOXIN-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR46762:SF1; NUCLEOREDOXIN-LIKE PROTEIN 2; 1.
DR Pfam; PF13905; Thioredoxin_8; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001811}.
FT DOMAIN 185..283
FT /note="Thioredoxin-like fold"
FT /evidence="ECO:0000259|Pfam:PF13905"
FT REGION 1..91
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 316 AA; 33661 MW; 08682F6AE2AF34B3 CRC64;
MSKLAPSLTT PPGSGTVSKA GSSAPGSGRR GTCCRLGRNW RGNAHGEGSP RVRAPGRGAR
GWAAERGGAS AGGEGAERGS GGCRGFPGLP RFPRALNSAS ADAALRSQKL XXXXXXXXXX
XXXXXXXXXX XXXXXXXXXX XXXXRRVAAR GEGGRPRSAM VDLLGGRRLL TREGAAVEAE
AALQNKVVAL YFAAGRCAPS RDFTPLLCDF YTALVGAAPR PAPFEVVFVS ADGSAEEMLD
FMRELHGAWL ALPFHDPYRH ELKKRYNITA TPKLVIVKQS GEVITSRGRK QIRERGLACF
QSWVEAAADV FQNFSG
//
