ID G1U0V8_RABIT Unreviewed; 163 AA.
AC G1U0V8;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Family with sequence similarity 162 member B {ECO:0000313|Ensembl:ENSOCUP00000022989.3};
GN Name=FAM162B {ECO:0000313|Ensembl:ENSOCUP00000022989.3};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000022989.3, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000022989.3, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke inbred {ECO:0000313|Ensembl:ENSOCUP00000022989.3,
RC ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000022989.3}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000022989.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the UPF0389 family.
CC {ECO:0000256|ARBA:ARBA00007363}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAGW02029257; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_008261637.1; XM_008263415.2.
DR AlphaFoldDB; G1U0V8; -.
DR STRING; 9986.ENSOCUP00000022989; -.
DR PaxDb; 9986-ENSOCUP00000022989; -.
DR Ensembl; ENSOCUT00000021437.3; ENSOCUP00000022989.3; ENSOCUG00000022415.3.
DR GeneID; 100344071; -.
DR CTD; 221303; -.
DR eggNOG; ENOG502SEVW; Eukaryota.
DR GeneTree; ENSGT00640000091497; -.
DR HOGENOM; CLU_122911_1_0_1; -.
DR InParanoid; G1U0V8; -.
DR OrthoDB; 2970852at2759; -.
DR TreeFam; TF323771; -.
DR Proteomes; UP000001811; Chromosome 12.
DR Bgee; ENSOCUG00000022415; Expressed in upper lobe of left lung and 14 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR009432; DUF1075.
DR PANTHER; PTHR13674; GROWTH AND TRANSFORMATION-DEPENDENT PROTEIN; 1.
DR PANTHER; PTHR13674:SF3; PROTEIN FAM162B; 1.
DR Pfam; PF06388; DUF1075; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001811};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 110..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 163 AA; 17670 MW; D17C47C8EE5681B5 CRC64;
MLRAVGSLVR LGLGRAVRCG PGARLEAARR LSPALPVHGL AYYSSGGVPS GSEQQGQAGK
VHRVPAQHKP SQFDKKILLW TGRFKSMEEI PTEVPPEMID AARNKARVKA CYIMIGLTII
ACFAVIASAK RAAERHESLT SWNLAKKAKW REEAALAAQA KTK
//
