ID   G1U104_RABIT            Unreviewed;       192 AA.
AC   G1U104;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   11-DEC-2019, sequence version 2.
DT   27-MAR-2024, entry version 55.
DE   SubName: Full=Transmembrane protein 11 {ECO:0000313|Ensembl:ENSOCUP00000023037.2};
GN   Name=TMEM11 {ECO:0000313|Ensembl:ENSOCUP00000023037.2};
OS   Oryctolagus cuniculus (Rabbit).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX   NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000023037.2, ECO:0000313|Proteomes:UP000001811};
RN   [1] {ECO:0000313|Ensembl:ENSOCUP00000023037.2, ECO:0000313|Proteomes:UP000001811}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Thorbecke {ECO:0000313|Proteomes:UP000001811};
RX   PubMed=21993624; DOI=10.1038/nature10530;
RA   Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA   Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA   Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA   Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA   Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA   Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA   Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA   Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA   Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA   Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA   Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA   Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA   Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA   Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA   Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT   "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL   Nature 478:476-482(2011).
RN   [2] {ECO:0000313|Ensembl:ENSOCUP00000023037.2}
RP   IDENTIFICATION.
RC   STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000023037.2};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- FUNCTION: Plays a role in mitochondrial morphogenesis.
CC       {ECO:0000256|ARBA:ARBA00002812}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC       inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane
CC       protein {ECO:0000256|ARBA:ARBA00004448}.
CC   -!- SIMILARITY: Belongs to the TMEM11 family.
CC       {ECO:0000256|ARBA:ARBA00006060}.
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DR   AlphaFoldDB; G1U104; -.
DR   PaxDb; 9986-ENSOCUP00000023037; -.
DR   Ensembl; ENSOCUT00000014097.3; ENSOCUP00000023037.2; ENSOCUG00000014103.3.
DR   eggNOG; ENOG502QUAI; Eukaryota.
DR   GeneTree; ENSGT00390000006617; -.
DR   HOGENOM; CLU_095460_0_0_1; -.
DR   TreeFam; TF324685; -.
DR   Proteomes; UP000001811; Unplaced.
DR   Bgee; ENSOCUG00000014103; Expressed in skeletal muscle tissue and 19 other cell types or tissues.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007005; P:mitochondrion organization; IEA:InterPro.
DR   InterPro; IPR026120; TMEM11.
DR   PANTHER; PTHR15099; PROTEIN PM1; 1.
DR   PANTHER; PTHR15099:SF2; TRANSMEMBRANE PROTEIN 11, MITOCHONDRIAL; 1.
DR   Pfam; PF14972; Mito_morph_reg; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001811};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
SQ   SEQUENCE   192 AA;  21765 MW;  67521368F1F63E5E CRC64;
     MTTWRRRRLV PGISGSIARE RVSLSATDCY IVHEIYNGEN AQDQFEYELE QALEAQYKYI
     VIEPTRIGDE TARWITVGNC LHKTAVLAGT ACLCTPWALP LDYSHYISLP AGVLSLACCT
     LYGISWQFDP CCKYQVEYDA YKLSRLPLHT LTSSTPVVLV RKDDLHRKRL HNTVALAALV
     YCVKKVYELC AV
//