ID G1U5F3_RABIT Unreviewed; 254 AA.
AC G1U5F3;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Potassium channel tetramerization domain containing 14 {ECO:0000313|Ensembl:ENSOCUP00000024632.2};
GN Name=KCTD14 {ECO:0000313|Ensembl:ENSOCUP00000024632.2};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000024632.2, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000024632.2, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke inbred {ECO:0000313|Ensembl:ENSOCUP00000024632.2,
RC ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000024632.2}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000024632.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAGW02008309; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_008261692.1; XM_008263470.2.
DR AlphaFoldDB; G1U5F3; -.
DR SMR; G1U5F3; -.
DR STRING; 9986.ENSOCUP00000024632; -.
DR PaxDb; 9986-ENSOCUP00000024632; -.
DR Ensembl; ENSOCUT00000005733.3; ENSOCUP00000024632.2; ENSOCUG00000005742.3.
DR GeneID; 100348285; -.
DR KEGG; ocu:100348285; -.
DR CTD; 65987; -.
DR eggNOG; KOG2723; Eukaryota.
DR GeneTree; ENSGT00940000160762; -.
DR HOGENOM; CLU_070345_1_0_1; -.
DR InParanoid; G1U5F3; -.
DR OrthoDB; 2912088at2759; -.
DR TreeFam; TF315332; -.
DR Proteomes; UP000001811; Chromosome 1.
DR Bgee; ENSOCUG00000005742; Expressed in prefrontal cortex and 12 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR PANTHER; PTHR14499:SF3; BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD14; 1.
DR PANTHER; PTHR14499; POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING; 1.
DR Pfam; PF02214; BTB_2; 1.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00022475};
KW Reference proteome {ECO:0000313|Proteomes:UP000001811}.
FT DOMAIN 31..128
FT /note="BTB"
FT /evidence="ECO:0000259|SMART:SM00225"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 254 AA; 28692 MW; 676875468FB44DA1 CRC64;
MTSLRSAPGS PASTSRAPAP PPVTDRQNII KVVELNVGGQ FYTTTLDTLR KFPDSKLAEM
FSGANLACRD AKGCFFIDRP GTYFGPILEY LRSGQLPTQH LPEVYREAQF YGIKPLVKLL
EDTPQIFGEQ VARRQFLLQV PGYSENLELL VRLARARAVA QRHSRVMVCV MPSEQHSAKY
QERPRTEEDT IVMHTPGMLE TDVRDLMDCV KMDLQNQGYR VTFSGPYTNS LFSTSSSRFA
PACACSFKFT FTWW
//
