ID G1U6B5_RABIT Unreviewed; 346 AA.
AC G1U6B5;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=CREB/ATF bZIP transcription factor {ECO:0000313|Ensembl:ENSOCUP00000024957.2};
GN Name=CREBZF {ECO:0000313|Ensembl:ENSOCUP00000024957.2};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000024957.2, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000024957.2, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke inbred {ECO:0000313|Ensembl:ENSOCUP00000024957.2,
RC ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000024957.2}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000024957.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAGW02008516; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1U6B5; -.
DR STRING; 9986.ENSOCUP00000024957; -.
DR PaxDb; 9986-ENSOCUP00000024957; -.
DR Ensembl; ENSOCUT00000016536.3; ENSOCUP00000024957.2; ENSOCUG00000016544.3.
DR eggNOG; ENOG502S3I0; Eukaryota.
DR GeneTree; ENSGT00390000016589; -.
DR HOGENOM; CLU_073094_0_0_1; -.
DR InParanoid; G1U6B5; -.
DR TreeFam; TF336153; -.
DR Proteomes; UP000001811; Chromosome 1.
DR Bgee; ENSOCUG00000016544; Expressed in uterus and 16 other cell types or tissues.
DR GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0090575; C:RNA polymerase II transcription regulator complex; IEA:Ensembl.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:Ensembl.
DR GO; GO:0045814; P:negative regulation of gene expression, epigenetic; IEA:Ensembl.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR GO; GO:0009615; P:response to virus; IEA:Ensembl.
DR Gene3D; 1.20.5.170; -; 1.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR Pfam; PF00170; bZIP_1; 1.
DR SUPFAM; SSF57959; Leucine zipper domain; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001811}.
FT DOMAIN 205..252
FT /note="BZIP"
FT /evidence="ECO:0000259|Pfam:PF00170"
FT REGION 1..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 156..202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 217..251
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 9..23
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 346 AA; 36300 MW; 4D1FA5D1A7EB73E0 CRC64;
MRHSLTKLLA ASGSDSPTRS ESPAPAEETA AAGSPGRQQP HGDADELEAG RGSRGGLAVR
APSPEEMEEE AIASVPGEET EDMDFLSGLE LADLLDPRQP DWHLEPGLSS PGPLSSSGGG
SDSGGLWRGD DDDEAAAAEM QRFSDLLQRL LNGIGGCSSS SDSGGGEKRR RKSPGGGGGG
GSGGGGGNDN TQAATKSPRK AAAAAARLNR LKKKEYVMGL ESRVRGLAAE NQELRVENRE
LSKRVQALQE ESRYLRAVLA NETGLARLLS RLSGVGLRLT TSLFRDSPAG DHDYALPVGK
QQQDVLEEDD SAGGVCLHVD KDKVSVEFCS ACARKASSSL KIFFFR
//
