ID G1U7P2_RABIT Unreviewed; 144 AA.
AC G1U7P2;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Cystatin like 1 {ECO:0000313|Ensembl:ENSOCUP00000025451.2};
GN Name=CSTL1 {ECO:0000313|Ensembl:ENSOCUP00000025451.2};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000025451.2, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000025451.2, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke inbred {ECO:0000313|Ensembl:ENSOCUP00000025451.2,
RC ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000025451.2}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000025451.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAGW02052344; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1U7P2; -.
DR SMR; G1U7P2; -.
DR STRING; 9986.ENSOCUP00000025451; -.
DR PaxDb; 9986-ENSOCUP00000025451; -.
DR Ensembl; ENSOCUT00000031818.2; ENSOCUP00000025451.2; ENSOCUG00000024430.2.
DR eggNOG; ENOG502SAEJ; Eukaryota.
DR GeneTree; ENSGT00900000141212; -.
DR HOGENOM; CLU_118168_0_1_1; -.
DR InParanoid; G1U7P2; -.
DR Proteomes; UP000001811; Chromosome 4.
DR Bgee; ENSOCUG00000024430; Expressed in testis and 2 other cell types or tissues.
DR GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:InterPro.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:Ensembl.
DR GO; GO:0140448; P:signaling receptor ligand precursor processing; IEA:Ensembl.
DR CDD; cd00042; CY; 1.
DR Gene3D; 3.10.450.10; -; 1.
DR InterPro; IPR042921; CSTL1.
DR InterPro; IPR000010; Cystatin_dom.
DR InterPro; IPR046350; Cystatin_sf.
DR PANTHER; PTHR47887; CYSTATIN-LIKE 1; 1.
DR PANTHER; PTHR47887:SF1; CYSTATIN-LIKE 1; 1.
DR Pfam; PF00031; Cystatin; 1.
DR SMART; SM00043; CY; 1.
DR SUPFAM; SSF54403; Cystatin/monellin; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001811};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..144
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5023871123"
FT DOMAIN 26..135
FT /note="Cystatin"
FT /evidence="ECO:0000259|SMART:SM00043"
SQ SEQUENCE 144 AA; 17047 MW; BE54629F26B2149B CRC64;
MEGGRWRVSL LVLMALTLVA KLGHFQRWEG FQEKPMSKKN MNSTLNFFIQ SYNNNSNDTY
LFRVQKLIRS QMQLTTGVEY KVTVKIGRTK CKRHSKKSSS CPLQSKKLKK SLICESLIYT
VPWMKYYQMW NNSCLETEAV RKFW
//
