ID G1U7Y7_RABIT Unreviewed; 95 AA.
AC G1U7Y7;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE RecName: Full=Small ubiquitin-related modifier {ECO:0000256|RuleBase:RU361190};
DE Short=SUMO {ECO:0000256|RuleBase:RU361190};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000025547.1, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000025547.1, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke {ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000025547.1}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000025547.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus, PML body
CC {ECO:0000256|ARBA:ARBA00004322}.
CC -!- SIMILARITY: Belongs to the ubiquitin family. SUMO subfamily.
CC {ECO:0000256|ARBA:ARBA00009185, ECO:0000256|RuleBase:RU361190}.
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DR RefSeq; XP_002710598.1; XM_002710552.3.
DR RefSeq; XP_002712592.1; XM_002712546.3.
DR RefSeq; XP_002722992.1; XM_002722946.3.
DR AlphaFoldDB; G1U7Y7; -.
DR SMR; G1U7Y7; -.
DR STRING; 9986.ENSOCUP00000025547; -.
DR PaxDb; 9986-ENSOCUP00000020851; -.
DR Ensembl; ENSOCUT00000003915.3; ENSOCUP00000025547.1; ENSOCUG00000028195.2.
DR GeneID; 100340132; -.
DR GeneID; 100344119; -.
DR GeneID; 100354027; -.
DR KEGG; ocu:100340132; -.
DR KEGG; ocu:100344119; -.
DR KEGG; ocu:100354027; -.
DR CTD; 6613; -.
DR eggNOG; KOG1769; Eukaryota.
DR GeneTree; ENSGT00950000182895; -.
DR HOGENOM; CLU_148322_2_1_1; -.
DR InParanoid; G1U7Y7; -.
DR OMA; IKRSTPM; -.
DR OrthoDB; 5132985at2759; -.
DR TreeFam; TF315116; -.
DR Proteomes; UP000001811; Unplaced.
DR Bgee; ENSOCUG00000028195; Expressed in embryo and 15 other cell types or tissues.
DR GO; GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
DR GO; GO:0016925; P:protein sumoylation; IEA:UniProt.
DR CDD; cd16115; Ubl_SUMO2_3_4; 1.
DR InterPro; IPR022617; Rad60/SUMO-like_dom.
DR InterPro; IPR000626; Ubiquitin-like_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR10562; SMALL UBIQUITIN-RELATED MODIFIER; 1.
DR PANTHER; PTHR10562:SF74; SMALL UBIQUITIN-RELATED MODIFIER 2-RELATED; 1.
DR Pfam; PF11976; Rad60-SLD; 1.
DR SMART; SM00213; UBQ; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50053; UBIQUITIN_2; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|RuleBase:RU361190};
KW Reference proteome {ECO:0000313|Proteomes:UP000001811};
KW Ubl conjugation pathway {ECO:0000256|RuleBase:RU361190}.
FT DOMAIN 16..93
FT /note="Ubiquitin-like"
FT /evidence="ECO:0000259|PROSITE:PS50053"
SQ SEQUENCE 95 AA; 10857 MW; F8F7321F49BEF08B CRC64;
MADEKPKEGV KTENNDHINL KVAGQDGSVV QFKIKRHTPL SKLMKAYCER QGLSMRQIRF
RFDGQPINES DTPAQLEMED EDTIDVFQQQ TGGVY
//
