ID G1VFR7_9BACT Unreviewed; 683 AA.
AC G1VFR7;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=HD domain-containing protein {ECO:0000259|PROSITE:PS51831};
GN ORFNames=HMPREF0666_02250 {ECO:0000313|EMBL:EGW46556.1};
OS Prevotella sp. C561.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=563031 {ECO:0000313|EMBL:EGW46556.1, ECO:0000313|Proteomes:UP000003086};
RN [1] {ECO:0000313|EMBL:EGW46556.1, ECO:0000313|Proteomes:UP000003086}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C561 {ECO:0000313|EMBL:EGW46556.1,
RC ECO:0000313|Proteomes:UP000003086};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Ward D., Feldgarden M., Gevers D., Sibley C.D., Field T.R.,
RA Grinwis M., Eshaghurshan C.S., Surette M.G., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Mehta T.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Prevotella sp. C561.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGW46556.1}.
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DR EMBL; ADCT01000087; EGW46556.1; -; Genomic_DNA.
DR RefSeq; WP_009012357.1; NZ_JH114148.1.
DR AlphaFoldDB; G1VFR7; -.
DR STRING; 563031.HMPREF0666_02250; -.
DR PATRIC; fig|563031.3.peg.2147; -.
DR eggNOG; COG1480; Bacteria.
DR HOGENOM; CLU_015767_1_1_10; -.
DR Proteomes; UP000003086; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR011624; Metal-dep_PHydrolase_7TM_extra.
DR InterPro; IPR011621; Metal-dep_PHydrolase_7TM_intra.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR36442; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR PANTHER; PTHR36442:SF1; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR Pfam; PF07698; 7TM-7TMR_HD; 1.
DR Pfam; PF07697; 7TMR-HDED; 1.
DR Pfam; PF01966; HD; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 265..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 320..337
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 342..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 386..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 475..569
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
SQ SEQUENCE 683 AA; 78129 MW; 5CC52CE1A21DA030 CRC64;
MIRFKNISSP YWRNMVSRMA LVIVAVVLIV LFLPRTQGKL FHYDEGKPWM YGQLIAKFDF
PIFKTEAALK VEKDSITKHF QPYYNINKTV EQKKIEQFRE AYKNGIPGLS EAYVDAIAHR
LHEIYEAGII DPQQYSTLAK DSNNLIRVVT GKQAVSVPIN KTYSTLGAYE QLFMDPLLGP
KRSVLQQCNL NDYIEANLVY DKDRSETEMN DMLSLIPQAS GMVLEGQRII DRGDIVDAKT
YRVLNSFEQA MEKRKATEDE ITSTFLGQTI YVLIFICLFT LYLALFRKDY FNKPRSISLL
YVMIVIYPIL TSLMMEHNIL SVYILPFSMA PIFFRVFMDS RTAFIGHITM VLICAVAVKY
QYEFIIVQIV AGLIAIYSLR ELSKRIQIFL TALLVTIGSA AVYLALQLIQ ADDLSKLDHT
MYYHFAVNGF FLLFTYPLML VIEKAFGFVS TVTMFELSNT NNELLRRLSE VAPGTFQHSI
TVGNLATEIA SRIGAKSQLV RTGALYHDIG KMLNPAFFTE NQAGINPHDK LNDLESARII
ISHVTEGLKL AEKYNLPREI KEFITTHHGT GLAKYFYIHY KNEHPDEEVN EDQFRYPGPN
PFTREQAILM MSDTVEAASR SLQEYTEESI SNLVNQLIDG QVADGKFTDC PITFRDITAA
KSVLIERLKA MYHTRIQYPQ LKV
//
